NCT04383314Completed
Targeting Hyaluronan Accumulation Through Exercise in T2DM
A Longitudinal, Single-center Study Investigating the Effects of Exercise on Hyaluronan Accumulation in Skeletal Muscle in Individuals With Type 2 Diabetes Mellitus
Source: ClinicalTrials.gov · Last updated 31 Jan 2025
Brief summary (registry, in English)
A pilot longitudinal study to examine hyaluronan (HA) accumulation in muscles of individuals with Type 2 diabetes mellitus (T2DM), and the effects of exercise on HA accumulation, muscle stiffness, strength, ankle joint mobility, and physical function. HA accumulation will be assessed non- invasively using magnetic resonance imaging.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 6 May 2020
- Start date
- 1 Sept 2021
- Primary completion date
- 31 May 2023
- Lead sponsor
- NYU Langone Health
- Diseases
- Type 2 diabetes
- NCT number
- NCT04383314
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 1 Sept 2021 to the primary completion date, 31 May 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindications to 3T whole body MRI scanners (e.g., pacemaker, cerebral aneurysm clip, cochlear implant, presence of shrapnel in strategic locations, metal in the eye, claustrophobia, or other problems).
Other illness
- Serious cardiac pathology or musculoskeletal problems that would limit exercise ability
- Current open wound or history of plantar ulcer for the last 3 months
- Stroke or other central nervous system pathology
- Stage 2 hypertension (resting blood pressure \>160 systolic or \>100 diastolic)
- Subjects with alcoholism, chronic drug use, chronic gastrointestinal disease, or renal or hepatic impairment
Other
- Partial foot amputations
- Inability to ambulate without assistive device
- Pregnant women and children
Who the study is looking for
- Be between the ages of 40 and 75
- Clinical diagnosis of Type 2 diabetes
- Have a BMI less than 40 kg/m2 (due to magnet bore restrictions)
- Able to walk unassisted
Age in the registry: 40 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| NYU Langone Health Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.