NCT04392544Active, not recruiting
Intestinal Inflammation in CF Patients
Interrogation of the Prevalence of Intestinal Inflammation in Cystic Fibrosis Patients and the Correlation with Abdominal Symptoms
Source: ClinicalTrials.gov · Last updated 20 Jan 2025
Brief summary (registry, in English)
Cystic Fibrosis (CF) is a disease that affects salt and water transport in multiple organs. Many CF patients suffer from abdominal pain and this could be due to intestinal inflammation. However, so far we do not know how many of the CF patients actually do have intestinal inflammation when looking at intestinal specimens. There is a proven connection between chronic inflammation and developing colorectal cancer and over the years more CF patients are developing colorectal cancer. Thus, it becomes increasingly important to look for the presence of intestinal inflammation in CF patients since early treatment may improve their symptoms and reduce the risk for colorectal cancer.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 13 May 2020
- Start date
- 11 Sept 2018
- Primary completion date
- 31 Mar 2024
- Lead sponsor
- The Hospital for Sick Children
- Diseases
- Cystic fibrosis
- NCT number
- NCT04392544
What you commit to
- Study type: Observational
- Planned participants: 100
- From 11 Sept 2018 to the primary completion date, 31 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any health condition, e.g. coagulopathy, sepsis, severe bacterial colitis that would increase the risk for perforation or bleeding when taking intestinal tissue biopsies.
Other
- Pediatric Cohort:
- Patients with the diagnosis of IBD.
- Patients during an episode of acute gastroenteritis or a pulmonary exacerbation.
- Adult cohort:
- Patients with the diagnosis of IBD.
Who the study is looking for
- Pediatric cohort:
- Diagnosis of CF
- Informed consent obtained
- Age 10-18 years
- Adult cohort:
- Diagnosis of CF
- Informed consent obtained
- Age ≥ 18 years
- Patient undergoing a colonoscopy for a clinical indication
Age in the registry: 10 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hospital for Sick Children Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.