NCT04395937Recruiting
SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training
Source: ClinicalTrials.gov · Last updated 14 Apr 2026
Brief summary (registry, in English)
The effects of regular exercise on asthma control has not yet been well demonstrated. The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 4 May 2020
- Start date
- 1 Sept 2020
- Primary completion date
- 1 Sept 2028
- Lead sponsor
- University of Liege
- Diseases
- Asthma
- NCT number
- NCT04395937
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Sept 2020 to the primary completion date, 1 Sept 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe uncontrolled hypertension
Other
- IMC \> 35
- severe osteoarthritis of the knees and hips
- unstable angor
Who the study is looking for
- asthmatic patient
- aged 18- 65 years
- ACQ \> 1.5
- stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Liège Coordinator of this site? Confirm its status | Liège | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.