NCT04404166CompletedPhase 3
Phone-based Intervention Under Nurse Guidance After Stroke 2
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
The overall objective of Phone-based Intervention under Nurse Guidance after Stroke II (PINGS-2) is to deploy a hybrid study design to firstly, demonstrate the efficacy of a theoretical-model-based, mHealth technology-centered, nurse-led, multi-level integrated approach to substantially improve longer term BP control among 500 recent stroke patients encountered at 10 hospitals in Ghana. Secondly, PINGS II seeks to develop an implementation strategy for routine integration and policy adoption of mhealth for post-stroke BP control in a LMIC setting. The investigators will leverage experience gained from the NIH Global Brain Disorders funded R21 pilot study (NS094033) to test efficacy of a refined, culturally-tailored, and potentially implementable intervention aimed at addressing the premier modifiable risk for stroke \& other key variables in an under-resourced system burdened by suboptimal care \& outcomes.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 500 (actual)
- First submitted
- 21 May 2020
- Start date
- 23 Oct 2020
- Primary completion date
- 5 Apr 2024
- Lead sponsor
- Northern California Institute of Research and Education
- Diseases
- Stroke
- NCT number
- NCT04404166
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 500
- From 23 Oct 2020 to the primary completion date, 5 Apr 2024
- 10 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- \- Any condition that would limit participation in follow up assessments, such as severe cognitive impairment/dementia (MMSE ≤24).
Who the study is looking for
- age ≥ 18 years (stroke is commoner above this age cut-off)
- male or females (sex is a biologic variable of interest)
- recent stroke (within one month of symptom onset)- stroke may be ischemic or hemorrhagic based on brain imaging or diagnosed clinically using the locally validated version of the 8-item questionnaire for verifying stroke free status (8-QVSFS) when neuroimaging is not feasible
- uncontrolled HTN (SBP ≥ 140 mmHg at both the last clinical encounter post-stroke and the eligibility screening visit) - SBP is used as the selection variable since most African hypertensives \<60 years have systolic or combination systolic/ diastolic HTN and for most patients, controlling SBP also results in DBP control
- patients or family carers should own a basic mobile phone that can receive text/audio messages.
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ankaase Methodist Hospital Coordinator of this site? Confirm its status | Aboaso | Ghana | Unknown status |
| Korle Bu Teaching Hospital Coordinator of this site? Confirm its status | Accra | Ghana | Unknown status |
| Agogo Presbyterian Hospital Coordinator of this site? Confirm its status | Agogo | Ghana | Unknown status |
| Cape Coast Teaching Hospital Coordinator of this site? Confirm its status | Cape Coast | Ghana | Unknown status |
| Kwame Nkrumah University of Science and Technology Coordinator of this site? Confirm its status | Kumasi | Ghana | Unknown status |
| Manhyia Government Hospital Coordinator of this site? Confirm its status | Kumasi | Ghana | Unknown status |
| Tafo Government Hospital Coordinator of this site? Confirm its status | Kumasi | Ghana | Unknown status |
| Kumasi South Hospital Coordinator of this site? Confirm its status | Kumasi | Ghana | Unknown status |
| Kwadaso SDA Hospital Coordinator of this site? Confirm its status | Kumasi | Ghana | Unknown status |
| Komfo Anokye Teaching Hospital Coordinator of this site? Confirm its status | Kumasi | Ghana | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.