NCT04417530CompletedPhase 2
Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma
A Phase 2 Open-label, Ascending Single and Repeat Dose Escalation Trial of Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma
Source: ClinicalTrials.gov · Last updated 3 Mar 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The primary objective is to determine the safety, tolerability, and preliminary efficacy of belzupacap sarotalocan for the treatment of primary indeterminate lesions and small choroidal melanoma (IL/CM).
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 22 (actual)
- First submitted
- 2 Jun 2020
- Start date
- 5 Aug 2020
- Primary completion date
- 22 Apr 2024
- Lead sponsor
- Aura Biosciences
- Diseases
- Melanoma
- NCT number
- NCT04417530
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 22
- From 5 Aug 2020 to the primary completion date, 22 Apr 2024
- 22 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have known contraindications or sensitivities to the study drug or laser
Other illness
- Active ocular disease
Who the study is looking for
- Clinical diagnosis of primary indeterminate lesion or small choroidal melanoma (IL/CM)
- Have no evidence of metastatic disease confirmed by imaging
- Be treatment naïve for IL/CM
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (22)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| W.K. Kellogg Eye Center - University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
| Emory Eye Center Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| UCHealth Eye Center Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
| Massachusetts Eye and Ear Infirmary Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Midwest Eye Institute Coordinator of this site? Confirm its status | Carmel | United States | Unknown status |
| University of Illinois At Chicago Illinois Eye and Ear Infirmary Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Texas Retina Associates Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Retina Consultants of Carolina, PA Coordinator of this site? Confirm its status | Greenville | United States | Unknown status |
| Retina Consultants of Houston Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| University of Iowa Department of Ophthalmology and Visual Sciences Coordinator of this site? Confirm its status | Iowa City | United States | Unknown status |
| UCLA Jules Stein Eye Institute Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
| University of Wisconsin Dept of Ophthalmology & Visual Sciences Coordinator of this site? Confirm its status | Madison | United States | Unknown status |
| Retina Center Coordinator of this site? Confirm its status | Minneapolis | United States | Unknown status |
| St. Thomas Health / Tennessee Retina, PC Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| Columbia University Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Dean McGee Eye Institute Coordinator of this site? Confirm its status | Oklahoma City | United States | Unknown status |
| Byers Eye Institute at Stanford University Coordinator of this site? Confirm its status | Palo Alto | United States | Unknown status |
| Wills Eye Hospital Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Oregon Health & Science University: Casey Eye Institute Coordinator of this site? Confirm its status | Portland | United States | Unknown status |
| Associated Retinal Consultants, PC Coordinator of this site? Confirm its status | Royal Oak | United States | Unknown status |
| Retina Associates of Florida Coordinator of this site? Confirm its status | Tampa | United States | Unknown status |
| Retina Associates SW, P.C. Coordinator of this site? Confirm its status | Tucson | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.