NCT04419584RecruitingPhase 2/3
Evaluate the Efficacy of Using Modified Qing-Ying Decoction in Atopic Dermatitis Children
A Randomized Placebo-Controlled Clinical Trial of an Innovative Herbal Formula for Atopic Dermatitis in Children: Evaluations of Modified Qing-Ying Decoction on Efficacy and Gut Microbiome
Source: ClinicalTrials.gov · Last updated 30 Jul 2026
Brief summary (registry, in English)
The study aims to evaluate the clinical efficacy and safety of the modified Qing-Ying Decoction (mQYD) for the treatment of subacute and chronic atopic dermatitis (AD) in children when compared to the placebo control through examining the clinical symptoms, quality of life, gut microbiome, and Chinese medicine body constitution. This is a parallel, randomized, placebo-controlled, double-blind clinical trial. Eligible subjects will be randomly allocated to receive oral mQYD granules or it's placebo granules. Subjects will have 12-week of treatment, and then a 4-week follow-up.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 64 (estimated)
- First submitted
- 4 Jun 2020
- Start date
- 10 Sept 2020
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Atopic dermatitis (eczema)
- NCT number
- NCT04419584
What you commit to
- Study type: Interventional · Phase 2/3
- Planned participants: 64
- From 10 Sept 2020 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having used oral corticosteroids, oral antibiotics, other immunosuppressive or any preparation of oral herbal medicines for the treatment of AD in the past month;
Other illness
- History of allergy to Chinese medicines;
- AD with Yang deficiency in syndrome differentiation, such as pale looking, always feeling cold, fatigue, chronic diarrhea with loose stool, urinary disorders such as urinary difficulty, excessive urination or incontinence
- Known overt bacterial infections in the skin;
- Known severe medical conditions, such as cardiovascular, liver or renal dysfunction or Diabetes Mellitus;
- Having been diagnosed with scabies, allergic contact dermatitis, seborrheic dermatitis or psoriasis; and
Lab values
- Has taken anti-coagulant or anti-platelet drugs in the past month.
- Known history of glucose-6-phosphate dehydrogenase (G6PD) deficiency
Other
- Known pregnancy;
- Has taken any probiotics, prebiotics in the last month
Who the study is looking for
- Age of 4 to 17 (Chinese only);
- With EASI ≥ 10;
- Subacute and chronic atopic dermatitis presenting with dry, scaly, erythematous papules and plaques; and
- Provide written informed consent form (signed by one of their parents)
Age in the registry: 4 years to 17 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Chinese University of Hong Kong Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.