NCT04421846Recruiting
Study of Pathophysiology of Status Epilepticus and Dysimmune Encephalitis
COLETTE : Study of the Pathophysiology of Status Epilepticus and Dysimmune Encephalitis and Identification of Valuable Biomarkers
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
COLETTE is an interventional study for which blood, cerebrospinal fluid and post-mortem tissues are collected in patients with status epilepticus or epilepsy associated to dysimmune encephalitis as well as in control patients, to better understand the pathophysiology of these severe epileptic disorders.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- First submitted
- 4 Jun 2020
- Start date
- 25 Nov 2020
- Primary completion date
- 1 Jun 2033
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Epilepsy
- NCT number
- NCT04421846
What you commit to
- Study type: Interventional
- Planned participants: 400
- From 25 Nov 2020 to the primary completion date, 1 Jun 2033
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with known neurodegenerative disease.
- Group 2:
- Patients with known neurodegenerative disease, brain tumor, severe head trauma, meningitis, subarachnoid hemorrhages, stroke.
Other
- Group 1:
- Women with known or clinically detected pregnancy.
- Patient deprived of liberty
- Women with known or clinically detected pregnancy.
- Patient deprived of liberty
- Patients have been already treated by corticoids or IgIV.
- Group 3:
- Women with known or clinically detected pregnancy.
- Patient deprived of liberty.
- Patients with status epilepticus.
Who the study is looking for
- Group 1:
- Patients aged 2 years or above, with status epilepticus.
- Affiliation to a French social security system excluding "Aide Médicale" Etat (AME).
- Patients or relatives have been informed and given free informed and written consent to participate
- Patients under legal protection (guardianship, curatorship) or not
- Group 2:
- Patients aged 2 years or above, with clinical signs of epilepsy associated to dysimmune encephalitis.
- Affiliation to a French social security system excluding "Aide Médicale" Etat (AME).
- Patients or relatives have been informed and given free informed and written consent to participate
- Patients under legal protection (guardianship, curatorship) or not
- Group 3:
- Patients aged 18 years or above, without status epilepticus and/or dysimmune encephalitis.
- Affiliation to a French social security system excluding "Aide Médicale" Etat (AME).
- Patients or relatives have been informed and given free informed and written consent to participate
- Patients under legal protection (guardianship, curatorship) or not
Age in the registry: 2 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital de la Pitié-Salpêtrière Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.