NCT04449198RecruitingEarly phase 1
Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1
Source: ClinicalTrials.gov · Last updated 28 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The proposed study is designed to test the hypothesis that treatment of resveratrol for 12 weeks will improve both endothelin-B receptor (aim 1) and skeletal muscle mitochondrial function (aim 2) in people with type 1 diabetes.
- Status (registry)
- Recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 11 Jun 2020
- Start date
- 14 Oct 2020
- Primary completion date
- 1 Jan 2027
- Lead sponsor
- Augusta University
- Diseases
- Type 1 diabetes
- NCT number
- NCT04449198
What you commit to
- Study type: Interventional · Early phase 1
- Planned participants: 24
- From 14 Oct 2020 to the primary completion date, 1 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of vasoactive medications
Other illness
- Clinical diagnosis of hepatic, cardiovascular, or renal disease
- Uncontrolled hypertension (\>140/90 mm Hg on therapy)
Lab values
- Uncontrolled diabetes (HbA1C \>12%)
Other
- Diabetic complications (i.e. neuropathy)
- Pregnancy
Who the study is looking for
- Men and premenopausal women
- All races
- Clinical diagnosis of insulin-dependent type 1 diabetes (patients only)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology Coordinator of this site? Confirm its status | Augusta | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.