NCT04454073Active, not recruiting
Investigation of Factors Associated With Preserved Cognitive Function in Bipolar Disorder
Source: ClinicalTrials.gov · Last updated 13 Jul 2026
Brief summary (registry, in English)
Bipolar disorder (BD) ïs the fourth leading cause of disability worldwide among young people. Differences in demographic and clinical characteristics between patients do not influence educational achievement and receipt of disability pension, indicating that there are other factors such as neurocognitive function that are of importance for maintaining occupational and social function. Research has shown that at the group level, cognitive deficits are present in euthymic BD patients, while approximately 30%-50% of BD patients is not different from healthy controls when it comes to cognitive function. There is however little knowledge of risk and resilience factors for cognitive impairment in BD. Factors likely to contribute to cognitive and functional outcomes in BD, such as sleep, obesity, biological rhythms, comorbid medical and psychiatric conditions are also understudied. While it has been customary to focus research on factors related to the negative illness trajectories, the overarching aim of the current project is to explore factors associated with favourable outcomes. This shift in research focus is essential to elucidate factors related to more preserved function since this represents a clear gap in knowledge today.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 87 (actual)
- First submitted
- 8 Jun 2020
- Start date
- Oct 2021
- Primary completion date
- May 2024
- Lead sponsor
- St. Olavs Hospital
- Diseases
- Bipolar disorder
- NCT number
- NCT04454073
What you commit to
- Study type: Observational
- Participants enrolled: 87
- From Oct 2021 to the primary completion date, May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Symptom level above inclusion criteria will be put on a waiting list, and if informed consent is given, will be included when symptom level is reduced.
- No Norwegian fluency.
Who the study is looking for
- Individuals aged \>=18 years who score \<= 16 on the MADRS or \<= 8 on the YMRS.
- Willing and able to give online informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bipolar and sleep outpatient clinic, Department of Østmarka, Division of Mental Health Care Coordinator of this site? Confirm its status | Trondheim | Norway | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.