NCT04459416Active, not recruitingPhase 3
Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma
Opioid-Sparing Pain Treatment In Myeloma And Lymphoma Patients Undergoing High-Dose Chemotherapy (OPTIMAL-HiChemo): Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 9 Oct 2026
Brief summary (registry, in English)
The purpose of this study is to find out whether acupuncture treatments can reduce the need for opioid medication when managing pain caused by chemotherapy. The study will compare the effects of adding acupuncture to usual pain management with those of usual pain management alone, in reducing opioid use by relieving pain. Researchers also want to find out more about the effects of acupuncture treatments on other symptoms caused by cancer treatments and quality of life.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 299 (actual)
- First submitted
- 1 Jul 2020
- Start date
- 30 Jun 2020
- Primary completion date
- 2 Jul 2024
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Diseases
- Hodgkin lymphoma, Multiple myeloma
- NCT number
- NCT04459416
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 299
- From 30 Jun 2020 to the primary completion date, 2 Jul 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- acupuncture within two weeks prior to HiChemo (to avoid residual effects of acupuncture)
Lab values
- absolute neutrophil count (ANC) of \<500/μl, platelet count of \<20,000/ μl or INR \>2.0
Other
- unable to provide informed consent
Who the study is looking for
- age 18 or older
- pathological diagnosis of MM, HD or NHL
- scheduled for high dose chemotherapy for auto-HSCT in the following month (30 days)
- not taking opioids regularly in the week prior to consent (one-time dosing of opioids for a painful procedure is allowed)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Memorial Sloan-Kettering Cancer Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Seattle Cancel Care Alliance (Data Collection Only) Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.