NCT04464122Recruiting
Rediscovering Biomarkers for the Diagnosis and Early Treatment Response in NEN (REBORN)
Rediscovering Biomarkers for the Diagnosis and Early Treatment Response in NEN. REBORN Study
Source: ClinicalTrials.gov · Last updated 3 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a multicentre, controlled, observational prospective study on new biomarkers, as immune profiling, angiogenetic markers and circRNA from TEPs in the diagnosis and in the evaluation of treatment response in pulmonary and gastro-entero-pancreatic NENs.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 60 (estimated)
- First submitted
- 3 Jul 2020
- Start date
- 14 Sept 2020
- Primary completion date
- 14 Sept 2025
- Lead sponsor
- University of Roma La Sapienza
- Diseases
- Neuroendocrine tumours
- NCT number
- NCT04464122
What you commit to
- Study type: Observational
- Planned participants: 60
- From 14 Sept 2020 to the primary completion date, 14 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe chronic kidney disease (stage 4-5);
- Other non-neuroendocrine malignancies.
Lab values
- Clinical or laboratory signs of significant respiratory, cardiological and hepatobiliary disease;
Who the study is looking for
- Histologically-proven NENs, locally advanced or metastatic, originating from pulmonary or gastro-entero-pancreatic (GEP) tract, candidate to first line medical therapy (study group);
- Patients affected by other non-malignant endocrine disease, e.g. benign thyroid disfunction (control group).
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Andrea M Isidori Coordinator of this site? Confirm its status | Rome | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.