NCT04469790Active, not recruiting
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
Testing the Efficacy of Multi-day Interruptions in Sedentary Behaviors on Metabolic, Cognitive, and Affective Outcomes in Youth at Risk for Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 15 Jun 2026
Brief summary (registry, in English)
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs. single bouts of sustained exercise on metabolic, cognitive, affective, and cardiac autonomic nervous system responses in children with overweight and obesity who are at risk for type 2 diabetes. The use of continuous glucose monitoring will provide insight into the daily and cumulative metabolic effects of each condition that have thus far not been studied. In-lab studies demonstrating sustained efficacy of this approach in ameliorating negative effects of sedentary behaviors in children are necessary for the optimization of field-based interventions. Given the lack of success of interventions to prevent obesity-related diseases and increasing rates of type 2 diabetes in children and its related healthcare costs, this study addresses a critical public health need by testing of novel intervention strategies to reduce obesity-related diseases in children with overweight and obesity.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 188 (estimated)
- First submitted
- 20 May 2020
- Start date
- 1 Mar 2022
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- University of Southern California
- Diseases
- Type 2 diabetes
- NCT number
- NCT04469790
What you commit to
- Study type: Interventional
- Planned participants: 188
- From 1 Mar 2022 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current or past anti-psychotic drug use that would affect metabolism
- Precocious puberty and/or receiving androgen and estrogen therapy
- Medication use known to affect body composition/weight
Other illness
- Significant cardiac or pulmonary disease likely to or resulting in hypoxia or decreased perfusion
- Diagnosis of T2DM and/or presence of other endocrinologic disorders leading to obesity (e.g., Cushing Syndrome)
- Non-diet treatment for hypertension or dyslipidemia
Who the study is looking for
- Age 8-11 years-old
- Good general health
- BMI≥85th percentile
Age in the registry: 8 years to 11 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Britni Ryan Belcher, PhD, MPH Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.