NCT04478006Recruiting
Advanced Translational Research on Childhood Leukemia
Driving Therapeutic Progress of Childhood Leukemia Through Advanced Translational Research With Immediate and Long-term Impact. Precision Medicine for Childhood Leukemia.
Source: ClinicalTrials.gov · Last updated 3 Feb 2026
Brief summary (registry, in English)
Prognosis of children with leukemia, the most common pediatric cancer, has improved markedly. Yet, relapse still occurs in 15-40% of patients with a probability of survival of \<50%, which is unlikely to be boosted by intensification of standard chemotherapy due to overwhelming toxicity. The advent of effective and safe targeted therapies for high-risk cases is therefore imperative. This study constitutes two research projects aiming at driving therapeutic advances.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 14 Jul 2020
- Start date
- 1 Jul 2020
- Primary completion date
- 1 Jun 2028
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Childhood cancers
- NCT number
- NCT04478006
What you commit to
- Study type: Observational
- Planned participants: 300
- From 1 Jul 2020 to the primary completion date, 1 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- List of inclusion criteria:
- acute lymphoblastic leukemia (ALL) or
- acute myeloid leukemia (AML) or
- 3 .mixed phenotype acute leukemia (MPAL) or
- 4\. juvenile myelomonocytic leukemia (JMML) or
- 5\. myelodysplastic syndromes (MDS) or
- 6\. normal bone marrow donor
- List of exclusion criteria:
- This study will not recruit subjects who are unable to understand English or Chinese.
- Patient or parent refusal
Age in the registry: - to 18 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hong Kong Children Hospital Coordinator of this site? Confirm its status | Hong Kong | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.