NCT04479514CompletedPhase 2
Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy
Source: ClinicalTrials.gov · Last updated 12 Jun 2026
Brief summary (registry, in English)
This research study is examining a preventive skin care regimen for children diagnosed with a brain tumor and receiving anti-cancer therapy with a MEK, Pan-RAF, or BRAF inhibitor.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 14 (actual)
- First submitted
- 15 Jul 2020
- Start date
- 1 Oct 2020
- Primary completion date
- 1 Jan 2024
- Lead sponsor
- Dana-Farber Cancer Institute
- Diseases
- Childhood cancers
- NCT number
- NCT04479514
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 14
- From 1 Oct 2020 to the primary completion date, 1 Jan 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treated with a BRAF, MEK or pan-RAF inhibitor in the last three months
Other illness
- Past or present allergic reaction to bleach
- Past or present allergic reactions to sunscreen and/or creams, lotions, emollients to be utilized in this study
Age
- Diagnosed with brain tumor at \> 18 years old
Other
- No data in medical records regarding treatment exposures
Who the study is looking for
- Diagnosed with a brain tumor between ages 6 months old -18 years old and will undergo treatment with at least one of the following:
- Targeted BRAF inhibitor therapy to treat the brain tumor
- Targeted MEK inhibitor therapy to treat the brain tumor
- Targeted pan-RAF inhibitor therapy to treat the brain tumor
- Subjects may participate in other studies, including therapeutic trials.
- Ability to comply with PSCR including sun protection, gentle skin care and every other day dilute bleach baths.
- Ability to understand and/or the willingness of their parent or legally authorized representative to sign a written informed consent document.
Age in the registry: 6 months to 18 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dana-Farber Cancer Institute Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Boston Children's Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.