NCT04481373Completed
Targeting HIV Retention and Improved Viral Load Through Engagement ('THRIVE')
Source: ClinicalTrials.gov · Last updated 14 Oct 2025
Brief summary (registry, in English)
Many people with HIV infection are not consistently engaged in outpatient HIV care, and avoidance, stigma and denial contribute to poor engagement in HIV care. This project will develop and pilot test a new intervention, "THRIVE," for hospitalized persons who are out of HIV care and endorse avoidance, to improve how well they stay in outpatient HIV care after discharge. If successfully developed, the intervention will undergo large scale testing in later studies and could improve the health of persons with HIV infection and help end the HIV epidemic in the United States.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 75 (actual)
- First submitted
- 9 Jul 2020
- Start date
- 3 Mar 2021
- Primary completion date
- 29 Feb 2024
- Lead sponsor
- Baylor College of Medicine
- Diseases
- HIV
- NCT number
- NCT04481373
What you commit to
- Study type: Interventional
- Participants enrolled: 75
- From 3 Mar 2021 to the primary completion date, 29 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- intending to use a source of HIV primary care other than TSHC after discharge, because their outcomes cannot be evaluated;
Other
- in the opinion of the primary medical team caring for the patient, likely to be discharged to an institutional setting, die in the hospital or enter hospice;
- incarcerated or expected to be discharged to prison or jail;
- enrolled in another research study with prospective follow-up;
- pregnant, since pregnant women receive additional efforts to be linked and retained in care;
- admitted with acute psychosis which would preclude informed consent or meaningful participation with the intervention.
Who the study is looking for
- Hospitalized at Ben Taub Hospital, Houston, TX;
- at least 18 years of age;
- able to speak English or Spanish;
- HIV infected;
- able to provide informed consent and participate in the study (patients who are temporarily unable to participate will be followed and approached for enrollment if and when they are cognitively and physically capable of consenting and participating);
- HIV VL\>1000 c/mL;
- never in care or currently out of HIV care, defined as not meeting the 'visit constancy' measure (≥1 completed HIV primary care visit at Thomas Street Health Center (TSHC), Houston, TX, in each of the three 4-month intervals preceding admission); or ≥2 "no shows" to HIV primary care visits at TSHC in the last year.
- endorse one of two avoidance coping statements with the highest factor loadings on the Avoidant Coping Subscale from the Coping with HIV/AIDS scale
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ben Taub Hospital Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.