Sign in

NCT04487639Completed

Presence of SARS-CoV-2 (COVID-19) in Semen: Impact on Fertility Preservation in Male Oncological Patients ?

Presence of SARS-CoV-2 in Semen: Impact on Fertility Preservation in Male Oncological Patients During the COVID-19 Pandemic ?

Source: ClinicalTrials.gov · Last updated 3 Aug 2026

Brief summary (registry, in English)

During the COVID-19 pandemic, the French Agency of Biomedicine has recommended maintaining fertility preservation for patients requiring immediate oncological treatments exhibiting gonadotoxic effects. However, no study has examined the presence of SARS-CoV-2 in sperm from cancer patients. This study aims therefore to detect the presence of SARS-CoV-2, specifically in the seminal fluid and the spermatozoa fractions of cancer patient semen. The investigators will determine if the virus presence in sperm is associated with its presence in the nasal swabs, COVID symptoms, specific serological profiles and particular oncological pathologies/treatments.

Status (registry)
Completed
Study type
Interventional
Enrollment
129 (actual)
First submitted
21 Jul 2020
Start date
10 Jul 2020
Primary completion date
2 Jul 2021
Lead sponsor
University Hospital, Clermont-Ferrand
NCT number
NCT04487639

What you commit to

  • Study type: Interventional
  • Participants enrolled: 129
  • From 10 Jul 2020 to the primary completion date, 2 Jul 2021
  • 16 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Non-emergency fertility preservation or treatment with low gonadotoxic risk

Other illness

  • Semen collection failure

Other

  • Azoospermia
  • Severe Oligo-Astheno-Teratozoospermia (OAT) or Cryptozoospermia

Who the study is looking for

  • Man above 18 years of age, of reproductive age, needing oncofertility preservation through spermatozoa cryopreservation prior to a putative gonadotoxic treatment during the COVID-19 pandemic.
  • Symptomatic and asymptomatic COVID-19 patients. A patient is considered as symptomatic if he presents one or several of the following clinical signs: fever, cough, cephalalgia, myalgia, diarrhea, anosmia, pharyngodynia.
  • A sufficient number of remaining spermatozoa straws to perform at least six ART attempts

Age in the registry: 18 years to 60 years · Sex: Male · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (16)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
AP-Hôpitaux de Paris - Hôpital Jean Verdier - Service de Biologie de la reproduction
Coordinator of this site? Confirm its status
BondyFranceUnknown status
AP-Hôpitaux de Paris - Hôpital Antoine Béclére - Service de Biologie de la reproduction et AMP DPI CECOS
Coordinator of this site? Confirm its status
ClamartFranceUnknown status
CHU de Clermont-Ferrand
Coordinator of this site? Confirm its status
Clermont-FerrandFranceUnknown status
CHU de Clermont-Ferrand - Laboratoire de Virologie
Coordinator of this site? Confirm its status
Clermont-FerrandFranceUnknown status
CHU de Dijon - Laboratoire de Biologie de la Reproduction-CECOS
Coordinator of this site? Confirm its status
DijonFranceUnknown status
CHU de Grenoble - Laboratoire d'Aide à la Procréation CECOS
Coordinator of this site? Confirm its status
GrenobleFranceUnknown status
Hospices Civils de Lyon - Service AMP-CECOS
Coordinator of this site? Confirm its status
LyonFranceUnknown status
Hôpital de la Conception - AP-Hôpitaux de Marseille - Service AMP-CECOS
Coordinator of this site? Confirm its status
MarseilleFranceUnknown status
CHU de Nancy - Laboratoire de biologie de la reproduction - CECOS
Coordinator of this site? Confirm its status
NancyFranceUnknown status
AP-Hôpitaux de Paris - Hôpital Cochin - Service d'Histologie-Embryologie-Biologie de la reproduction
Coordinator of this site? Confirm its status
ParisFranceUnknown status
AP-Hôpitaux de Paris - Hôpital Tenon - Service de Biologie de la reproduction - CECOS
Coordinator of this site? Confirm its status
ParisFranceUnknown status
Centre Hospitalier intercommunal (CHI) de Poissy Saint Germain en Laye
Coordinator of this site? Confirm its status
PoissyFranceUnknown status
CHU de Reims - Service de Biologie de la Reproduction - CECOS Champagne-Ardenne de Reims
Coordinator of this site? Confirm its status
ReimsFranceUnknown status
CHU de Rouen Normandie - Service Biologie de la Reproduction-CECOS
Coordinator of this site? Confirm its status
RouenFranceUnknown status
CHU de Strasbourg - Service de Biologie de la reproduction
Coordinator of this site? Confirm its status
StrasbourgFranceUnknown status
CHU de Toulouse - CECOS Midi-Pyrénées
Coordinator of this site? Confirm its status
ToulouseFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.