NCT04487639Completed
Presence of SARS-CoV-2 (COVID-19) in Semen: Impact on Fertility Preservation in Male Oncological Patients ?
Presence of SARS-CoV-2 in Semen: Impact on Fertility Preservation in Male Oncological Patients During the COVID-19 Pandemic ?
Source: ClinicalTrials.gov · Last updated 3 Aug 2026
Brief summary (registry, in English)
During the COVID-19 pandemic, the French Agency of Biomedicine has recommended maintaining fertility preservation for patients requiring immediate oncological treatments exhibiting gonadotoxic effects. However, no study has examined the presence of SARS-CoV-2 in sperm from cancer patients. This study aims therefore to detect the presence of SARS-CoV-2, specifically in the seminal fluid and the spermatozoa fractions of cancer patient semen. The investigators will determine if the virus presence in sperm is associated with its presence in the nasal swabs, COVID symptoms, specific serological profiles and particular oncological pathologies/treatments.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 129 (actual)
- First submitted
- 21 Jul 2020
- Start date
- 10 Jul 2020
- Primary completion date
- 2 Jul 2021
- Lead sponsor
- University Hospital, Clermont-Ferrand
- NCT number
- NCT04487639
What you commit to
- Study type: Interventional
- Participants enrolled: 129
- From 10 Jul 2020 to the primary completion date, 2 Jul 2021
- 16 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Non-emergency fertility preservation or treatment with low gonadotoxic risk
Other illness
- Semen collection failure
Other
- Azoospermia
- Severe Oligo-Astheno-Teratozoospermia (OAT) or Cryptozoospermia
Who the study is looking for
- Man above 18 years of age, of reproductive age, needing oncofertility preservation through spermatozoa cryopreservation prior to a putative gonadotoxic treatment during the COVID-19 pandemic.
- Symptomatic and asymptomatic COVID-19 patients. A patient is considered as symptomatic if he presents one or several of the following clinical signs: fever, cough, cephalalgia, myalgia, diarrhea, anosmia, pharyngodynia.
- A sufficient number of remaining spermatozoa straws to perform at least six ART attempts
Age in the registry: 18 years to 60 years · Sex: Male · Does not accept healthy volunteers
Sites (16)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| AP-Hôpitaux de Paris - Hôpital Jean Verdier - Service de Biologie de la reproduction Coordinator of this site? Confirm its status | Bondy | France | Unknown status |
| AP-Hôpitaux de Paris - Hôpital Antoine Béclére - Service de Biologie de la reproduction et AMP DPI CECOS Coordinator of this site? Confirm its status | Clamart | France | Unknown status |
| CHU de Clermont-Ferrand Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| CHU de Clermont-Ferrand - Laboratoire de Virologie Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| CHU de Dijon - Laboratoire de Biologie de la Reproduction-CECOS Coordinator of this site? Confirm its status | Dijon | France | Unknown status |
| CHU de Grenoble - Laboratoire d'Aide à la Procréation CECOS Coordinator of this site? Confirm its status | Grenoble | France | Unknown status |
| Hospices Civils de Lyon - Service AMP-CECOS Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
| Hôpital de la Conception - AP-Hôpitaux de Marseille - Service AMP-CECOS Coordinator of this site? Confirm its status | Marseille | France | Unknown status |
| CHU de Nancy - Laboratoire de biologie de la reproduction - CECOS Coordinator of this site? Confirm its status | Nancy | France | Unknown status |
| AP-Hôpitaux de Paris - Hôpital Cochin - Service d'Histologie-Embryologie-Biologie de la reproduction Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| AP-Hôpitaux de Paris - Hôpital Tenon - Service de Biologie de la reproduction - CECOS Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Centre Hospitalier intercommunal (CHI) de Poissy Saint Germain en Laye Coordinator of this site? Confirm its status | Poissy | France | Unknown status |
| CHU de Reims - Service de Biologie de la Reproduction - CECOS Champagne-Ardenne de Reims Coordinator of this site? Confirm its status | Reims | France | Unknown status |
| CHU de Rouen Normandie - Service Biologie de la Reproduction-CECOS Coordinator of this site? Confirm its status | Rouen | France | Unknown status |
| CHU de Strasbourg - Service de Biologie de la reproduction Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
| CHU de Toulouse - CECOS Midi-Pyrénées Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.