NCT04497597Completed
A Study of Oral Upadacitinib Tablets to Assess Treatment Patterns, Achievement of Treatment Targets and Maintenance of Response in Adult Participants With Moderate to Severe Rheumatoid Arthritis
Upadacitinib Treatment Patterns, Achievement of Treatment Targets and Maintenance of Response in Moderate to Severe Rheumatoid Arthritis Patients in Real-World Practice (UPHOLD)
Source: ClinicalTrials.gov · Last updated 13 Apr 2025
Brief summary (registry, in English)
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally managed, with sustained clinical remission rarely achieved. This study will assess the treatment patterns, achievement of treatment targets and maintenance of response. Upadacitinib is a drug approved for the treatment of moderately to severely active rheumatoid arthritis. Adult participants with moderate to severe RA who have been prescribed upadacitinib by their physicians will be enrolled. Approximately, 1660 participants will be enrolled this study, worldwide. Participants will not receive Upadacitinib as part of this study, but will be followed for response to treatment for up to 24 months. There may be higher burden for participants in this trial compared to their standard of care. Participants will attend regular visits, every 3 months, during the course of the study at a hospital or clinic and will be asked to provide additional information by questionnaire at each visit.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1532 (actual)
- First submitted
- 30 Jul 2020
- Start date
- Oct 2020
- Primary completion date
- May 2024
- Lead sponsor
- AbbVie
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT04497597
What you commit to
- Study type: Observational
- Participants enrolled: 1532
- From Oct 2020 to the primary completion date, May 2024
- 263 sites in 19 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- \- Prior treatment with Upadacitinib.
Who the study is looking for
- Confirmed diagnosis of moderate to severe active Rheumatoid Arthritis (RA).
- Physician decision on patient treatment with upadacitinib must have been reached prior to and independently of recruitment in the study.
- Upadacitinib prescribed in accordance to the applicable approved label and local regulatory and reimbursement policies.
- French Participants Only: Taking oral glucocorticoids ≥5 mg/day of prednisone or equivalent for at least 3 months prior to study start.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (263)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cleveland Clinic Abu Dhabi /ID# 223176 Coordinator of this site? Confirm its status | Abu Dhabi | United Arab Emirates | Unknown status |
| Drt Sulaiman Al Habib Hospital /ID# 226575 Coordinator of this site? Confirm its status | Dubai | United Arab Emirates | Unknown status |
| Integrated Rheumatology and Arthritis Center /ID# 223177 Coordinator of this site? Confirm its status | Dubai | United Arab Emirates | Unknown status |
| Departnent of Medicine-Rheumatology Al Baraha Hospital and Al Qasmi Hospital Min /ID# 223178 Coordinator of this site? Confirm its status | Dubai | United Arab Emirates | Unknown status |
| DOM Centro de Reumatologia /ID# 222194 Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Unknown status |
| CIER Centro de Investigaciones en Enfermedades Reumaticas /ID# 231769 Coordinator of this site? Confirm its status | Ciudad Autonoma de Buenos Aire | Argentina | Unknown status |
| Organizacion Medica de Investigacion (OMI) /ID# 222187 Coordinator of this site? Confirm its status | Ciudad Autonoma de Buenos Aire | Argentina | Unknown status |
| Instituto Medico Strusberg /ID# 222189 Coordinator of this site? Confirm its status | Córdoba | Argentina | Unknown status |
| Hospital Italiano La Plata /ID# 222190 Coordinator of this site? Confirm its status | La Plata | Argentina | Unknown status |
| CER Instituto Medico /ID# 222193 Coordinator of this site? Confirm its status | Quilmes | Argentina | Unknown status |
| Instituto CAICI S.R.L /ID# 222191 Coordinator of this site? Confirm its status | Rosario | Argentina | Unknown status |
| CIMER Centro Integral de Medicina Respiratoria /ID# 222188 Coordinator of this site? Confirm its status | San Miguel de Tucumán | Argentina | Unknown status |
| Instituto de Cardiologia /ID# 226634 Coordinator of this site? Confirm its status | Santiago del Estero | Argentina | Unknown status |
| Dr. Georg Kurtz /ID# 225477 Coordinator of this site? Confirm its status | Gleisdorf | Austria | Unknown status |
| Ordination Dr. Leeb /ID# 224293 Coordinator of this site? Confirm its status | Hollabrunn | Austria | Unknown status |
| Klinikum Klagenfurt am Wörthersee /ID# 239628 Coordinator of this site? Confirm its status | Klagenfurt | Austria | Unknown status |
| Dr. Maya Thun /ID# 224299 Coordinator of this site? Confirm its status | Vienna | Austria | Unknown status |
| Ordination Doz. Grisar /ID# 224298 Coordinator of this site? Confirm its status | Vienna | Austria | Unknown status |
| Rheuma-Zentrum Wien-Oberlaa GmbH /ID# 227853 Coordinator of this site? Confirm its status | Vienna | Austria | Unknown status |
| Private Practice - Scott Walter Graf /ID# 223958 Coordinator of this site? Confirm its status | Adelaide | Australia | Unknown status |
| Genesis Research Services /ID# 224060 Coordinator of this site? Confirm its status | Broadmeadow | Australia | Unknown status |
| Emeritus Research /ID# 223883 Coordinator of this site? Confirm its status | Camberwell | Australia | Unknown status |
| Joint West Rheumatology /ID# 223886 Coordinator of this site? Confirm its status | Murdoch | Australia | Unknown status |
| BJC Health /ID# 223884 Coordinator of this site? Confirm its status | Parramatta | Australia | Unknown status |
| Onze Lieve Vrouw Hospital /ID# 223042 Coordinator of this site? Confirm its status | Aalst | Belgium | Unknown status |
| Algemeen Stedelijk Ziekenhuis /ID# 224121 Coordinator of this site? Confirm its status | Aalst | Belgium | Unknown status |
| AZ Sint-Jan Brugge /ID# 223713 Coordinator of this site? Confirm its status | Bruges | Belgium | Unknown status |
| AZ Sint Lucas /ID# 223093 Coordinator of this site? Confirm its status | Bruges | Belgium | Unknown status |
| CHU Saint Pierre /ID# 223041 Coordinator of this site? Confirm its status | Brussels | Belgium | Unknown status |
| Rhumaconsult SPRL /ID# 221825 Coordinator of this site? Confirm its status | Charleroi | Belgium | Unknown status |
| Reumacentrum /ID# 222799 Coordinator of this site? Confirm its status | Genk | Belgium | Unknown status |
| ReumaClinic /ID# 221353 Coordinator of this site? Confirm its status | Genk | Belgium | Unknown status |
| Maertens, Gistel, BE /ID# 221823 Coordinator of this site? Confirm its status | Gistel | Belgium | Unknown status |
| Duplicate_CHU UCL Namur - site Godinne /ID# 222797 Coordinator of this site? Confirm its status | Godinne | Belgium | Unknown status |
| Reuma Instituut Hasselt /ID# 221822 Coordinator of this site? Confirm its status | Hasselt | Belgium | Unknown status |
| CHU de Liege /ID# 222201 Coordinator of this site? Confirm its status | Liège | Belgium | Unknown status |
| AZ Alma Campus Sijsele /ID# 222214 Coordinator of this site? Confirm its status | Sijsele | Belgium | Unknown status |
| Private practice Sint-Niklaas /ID# 224123 Coordinator of this site? Confirm its status | Sint-Niklaas | Belgium | Unknown status |
| Kantonsspital Aarau AG /ID# 222354 Coordinator of this site? Confirm its status | Aarau | Switzerland | Unknown status |
| Universitätsspital Basel /ID# 224160 Coordinator of this site? Confirm its status | Basel Town | Switzerland | Unknown status |
| Inselspital, Universitaetsspital Bern /ID# 224951 Coordinator of this site? Confirm its status | Bern | Switzerland | Unknown status |
| HFR Fribourg - Hôpital cantonal /ID# 224163 Coordinator of this site? Confirm its status | Fribourg | Switzerland | Unknown status |
| CHUV, Centre hospitalier universitaire vaudois /ID# 224161 Coordinator of this site? Confirm its status | Lausanne | Switzerland | Unknown status |
| Kantonsspital St. Gallen /ID# 224158 Coordinator of this site? Confirm its status | Sankt Gallen | Switzerland | Unknown status |
| Rheumatologisches Versorgungszentrum Weinfelden /ID# 222346 Coordinator of this site? Confirm its status | Weinfelden | Switzerland | Unknown status |
| ACURA Rheumazentrum Baden-Bade /ID# 225225 Coordinator of this site? Confirm its status | Baden-Baden | Germany | Unknown status |
| Rheumapraxis Prof Dr Karin Manger /ID# 224086 Coordinator of this site? Confirm its status | Bamberg | Germany | Unknown status |
| Praxis fuer Rheumatologie und Innere Medizin /ID# 225222 Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
| Eisterhues, Braunschweig, DE /ID# 225186 Coordinator of this site? Confirm its status | Braunschweig | Germany | Unknown status |
| Dres. Karger/Baerlecken /ID# 224809 Coordinator of this site? Confirm its status | Cologne | Germany | Unknown status |
| Rheumatologie in Veedel /ID# 224999 Coordinator of this site? Confirm its status | Cologne | Germany | Unknown status |
| Praxis Dilltal /ID# 226925 Coordinator of this site? Confirm its status | Ehringshausen | Germany | Unknown status |
| MVZ Ambulantes Rheumazentrum Erfurt /ID# 224812 Coordinator of this site? Confirm its status | Erfurt | Germany | Unknown status |
| Helios Fachklinik Vogelsang-Gommern /ID# 222949 Coordinator of this site? Confirm its status | Gommern | Germany | Unknown status |
| Asklepios MVZ Nord SH GmbH /ID# 225048 Coordinator of this site? Confirm its status | Hamburg | Germany | Unknown status |
| Heilig, Heidelberg, DE /ID# 225223 Coordinator of this site? Confirm its status | Heidelberg | Germany | Unknown status |
| Praxis internistische Rheumatologie /ID# 239226 Coordinator of this site? Confirm its status | Leipzig | Germany | Unknown status |
| Dres. Teipel/Toussaint/Saech /ID# 226923 Coordinator of this site? Confirm its status | Leverkusen | Germany | Unknown status |
| Aurich & Sieburg, Magdeburg /ID# 230701 Coordinator of this site? Confirm its status | Magdeburg | Germany | Unknown status |
| Die Fachaerzte im Rottal - Nephrologie, Rheumatologie /ID# 223866 Coordinator of this site? Confirm its status | Pfarrkirchen | Germany | Unknown status |
| MVZ für Rheumatologie Dr. M. Welcker /ID# 226926 Coordinator of this site? Confirm its status | Planegg | Germany | Unknown status |
| Rheumatologische-Immunologische Praxis Templin /ID# 226924 Coordinator of this site? Confirm its status | Templin | Germany | Unknown status |
| Krankenhaus der Barmherzigen Brüder Trier /ID# 226927 Coordinator of this site? Confirm its status | Trier | Germany | Unknown status |
| Praxis Dr. Haas /ID# 225187 Coordinator of this site? Confirm its status | Tübingen | Germany | Unknown status |
| Complejo Hospitalario Universitario A Coruña /ID# 231818 Coordinator of this site? Confirm its status | A Coruña | Spain | Unknown status |
| Hospital Universitario Torrecardenas /ID# 241931 Coordinator of this site? Confirm its status | Almería | Spain | Unknown status |
| Hospital Perpetuo Socorro /ID# 231827 Coordinator of this site? Confirm its status | Badajoz | Spain | Unknown status |
| Hospital Parc de Salut del Mar /ID# 240000 Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital General de Granollers /ID# 238778 Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital Santa Creu i Sant Pau /ID# 231821 Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital Ernest Lluch Martin /ID# 238779 Coordinator of this site? Confirm its status | Calatayud | Spain | Unknown status |
| Hospital General Universitario Santa Lucia /ID# 238780 Coordinator of this site? Confirm its status | Cartagena | Spain | Unknown status |
| Hospital Universitario Reina Sofia /ID# 231843 Coordinator of this site? Confirm its status | Córdoba | Spain | Unknown status |
| Hospital Clinico Universitario Virgen de la Arrixaca /ID# 231847 Coordinator of this site? Confirm its status | El Palmar | Spain | Unknown status |
| Hospital Universitario de Getafe /ID# 231825 Coordinator of this site? Confirm its status | Getafe | Spain | Unknown status |
| Hospital Universitario Virgen de las Nieves /ID# 231841 Coordinator of this site? Confirm its status | Granada | Spain | Unknown status |
| Hospital Juan Ramon Jimenez /ID# 231840 Coordinator of this site? Confirm its status | Huelva | Spain | Unknown status |
| Hospital Universitario de Jaen /ID# 231842 Coordinator of this site? Confirm its status | Jaén | Spain | Unknown status |
| Hospital Universitario de Jerez de la Frontera /ID# 231844 Coordinator of this site? Confirm its status | Jerez de la Frontera | Spain | Unknown status |
| Hospital Rafael Mendez /ID# 231846 Coordinator of this site? Confirm its status | Lorca | Spain | Unknown status |
| Hospital Universitario Ramon y Cajal /ID# 241901 Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Hospital Universitario Virgen de la Victoria /ID# 240150 Coordinator of this site? Confirm its status | Málaga | Spain | Unknown status |
| Hospital de Mérida /ID# 231826 Coordinator of this site? Confirm its status | Mérida | Spain | Unknown status |
| Hospital Virgen del Puerto /ID# 240149 Coordinator of this site? Confirm its status | Plasencia | Spain | Unknown status |
| Hospital Universitario Canarias /ID# 231848 Coordinator of this site? Confirm its status | San Cristóbal de La Laguna | Spain | Unknown status |
| Hospital Universitario Virgen Macarena /ID# 231837 Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
| Hospital Universitario Virgen de Valme /ID# 231838 Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
| Hospital Universitario Virgen del Rocio /ID# 231836 Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
| Hospital Universitari Mútua Terrassa /ID# 231822 Coordinator of this site? Confirm its status | Terrassa | Spain | Unknown status |
| Hospital Xeral Cies (CHUVI) /ID# 231819 Coordinator of this site? Confirm its status | Vigo | Spain | Unknown status |
| Hospital de Viladecans /ID# 231823 Coordinator of this site? Confirm its status | Viladecans | Spain | Unknown status |
| Hospital Royo Villanova /ID# 231824 Coordinator of this site? Confirm its status | Zaragoza | Spain | Unknown status |
| CH du Pays d'AIX /ID# 229561 Coordinator of this site? Confirm its status | Aix-en-Provence | France | Unknown status |
| Cabinet medical /ID# 225366 Coordinator of this site? Confirm its status | Aix-les-Bains | France | Unknown status |
| Cabinet medical /ID# 224850 Coordinator of this site? Confirm its status | Albi | France | Unknown status |
| CHU Amiens-Picardie Site Sud /ID# 222444 Coordinator of this site? Confirm its status | Amiens | France | Unknown status |
| Centre Hospitalier d'Angouleme /ID# 226064 Coordinator of this site? Confirm its status | Angoulême | France | Unknown status |
| Cabinet Novel d'Annecy /ID# 232310 Coordinator of this site? Confirm its status | Annecy | France | Unknown status |
| Centre Hospitalier d'Arras /ID# 223172 Coordinator of this site? Confirm its status | Arras | France | Unknown status |
| CHU de Besancon - Jean Minjoz /ID# 222463 Coordinator of this site? Confirm its status | Besançon | France | Unknown status |
| Hopital Avicenne - APHP /ID# 224248 Coordinator of this site? Confirm its status | Bobigny | France | Unknown status |
| CHU Bordeaux - Hopital Pellegrin /ID# 224837 Coordinator of this site? Confirm its status | Bordeaux | France | Unknown status |
| Centre Hospitalier de Boulogne Sur Mer /ID# 222991 Coordinator of this site? Confirm its status | Boulogne-sur-Mer | France | Unknown status |
| Hopital de la Cavale Blanche /ID# 222462 Coordinator of this site? Confirm its status | Brest | France | Unknown status |
| cabinet liberal- Dr CORNILLE /ID# 227869 Coordinator of this site? Confirm its status | Caen | France | Unknown status |
| Centre Hospitalier Jean Rougie /ID# 224242 Coordinator of this site? Confirm its status | Cahors | France | Unknown status |
| Infirmerie Protestante /ID# 222438 Coordinator of this site? Confirm its status | Caluire-et-Cuire | France | Unknown status |
| CH Cannes - les Broussailles /ID# 226160 Coordinator of this site? Confirm its status | Cannes | France | Unknown status |
| CHRU Tours - Hopital Trousseau /ID# 222445 Coordinator of this site? Confirm its status | Chambray-lès-Tours | France | Unknown status |
| Centre Hospitalier de CHOLET /ID# 222455 Coordinator of this site? Confirm its status | Cholet | France | Unknown status |
| Hia Percy /Id# 225642 Coordinator of this site? Confirm its status | Clamart | France | Unknown status |
| CHU Clermont Ferrand - Hopital Gabriel Montpied /ID# 223801 Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| Cabinet liberal - Compiegne - Dr Banse /ID# 227099 Coordinator of this site? Confirm its status | Compiègne | France | Unknown status |
| C. H. Sud Francilien /ID# 222446 Coordinator of this site? Confirm its status | Corbeil-Essonnes | France | Unknown status |
| CHU Dijon /ID# 223799 Coordinator of this site? Confirm its status | Dijon | France | Unknown status |
| Cabinet medical /ID# 225142 Coordinator of this site? Confirm its status | Haguenau | France | Unknown status |
| Centre Hospitalier de Laon /ID# 224857 Coordinator of this site? Confirm its status | Laon | France | Unknown status |
| CH La Rochelle - Hopital Saint Louis /ID# 224240 Coordinator of this site? Confirm its status | La Rochelle | France | Unknown status |
| CHD Vendée- La Roche-sur-Yon - Les Oudairies /ID# 229086 Coordinator of this site? Confirm its status | La Roche-sur-Yon | France | Unknown status |
| CHU Grenoble - Hopital Michallon /ID# 223211 Coordinator of this site? Confirm its status | La Tronche | France | Unknown status |
| CH Emile Roux Le Puy en Velay /ID# 223688 Coordinator of this site? Confirm its status | Le Puy-en-Velay | France | Unknown status |
| Cabinet médical /ID# 225000 Coordinator of this site? Confirm its status | Les Abrets En Dauphine | France | Unknown status |
| CHU Lille - Hôpital Roger Salengro /ID# 223170 Coordinator of this site? Confirm its status | Lille | France | Unknown status |
| CHU Limoges - Dupuytren 1 /ID# 222457 Coordinator of this site? Confirm its status | Limoges | France | Unknown status |
| Clinique de la Sauvegarde /ID# 223424 Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
| Hopital Saint Joseph /ID# 227221 Coordinator of this site? Confirm its status | Marseille | France | Unknown status |
| Cabinet de rhumatologie /ID# 227740 Coordinator of this site? Confirm its status | Mennecy | France | Unknown status |
| CH Princesse Grace /ID# 222451 Coordinator of this site? Confirm its status | Monaco | France | Unknown status |
| Ch Montauban /Id# 231854 Coordinator of this site? Confirm its status | Montauban | France | Unknown status |
| ELSAN - Clinique du Pont de Chaume /ID# 224898 Coordinator of this site? Confirm its status | Montauban | France | Unknown status |
| CHU Montpellier - Hopital Saint Eloi /ID# 223394 Coordinator of this site? Confirm its status | Montpellier | France | Unknown status |
| Clinique Beau Soleil /ID# 224238 Coordinator of this site? Confirm its status | Montpellier | France | Unknown status |
| CHU Montpellier - Hopital Saint Eloi /ID# 222452 Coordinator of this site? Confirm its status | Montpellier | France | Unknown status |
| CH des Pays de Morlaix /ID# 223795 Coordinator of this site? Confirm its status | Morlaix | France | Unknown status |
| Polyclinique saint Odilon /ID# 225576 Coordinator of this site? Confirm its status | Moulins | France | Unknown status |
| Ch Mulhouse /Id# 223442 Coordinator of this site? Confirm its status | Mulhouse | France | Unknown status |
| CHU de Nantes, Hotel Dieu -HME /ID# 225787 Coordinator of this site? Confirm its status | Nantes | France | Unknown status |
| CHU Nice -Hopital Pasteur /ID# 222460 Coordinator of this site? Confirm its status | Nice | France | Unknown status |
| CH Georges Renon /ID# 225197 Coordinator of this site? Confirm its status | Niort | France | Unknown status |
| Centre Hospitalier Régional d'Orléans - Hôpital de la Source /ID# 223591 Coordinator of this site? Confirm its status | Orléans | France | Unknown status |
| Centre de Soins Osteoarticulaires Ambulatoires /ID# 224737 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Hopitaux Universitaires Paris Centre-Hopital Cochin /ID# 222986 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| GH Diaconesses Croix Saint-Simon /ID# 229126 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| AP-HP - Hopital Saint-Antoine /ID# 222441 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Hopital Pitie Salpetriere /ID# 222443 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| AP-HP - Hopital Bichat - Claude-Bernard /ID# 222449 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Cabinet medical /ID# 224855 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Cabinet libéral du Dr PAUPIERE /ID# 238723 Coordinator of this site? Confirm its status | Péronne | France | Unknown status |
| HCL - Hopital Lyon Sud /ID# 222447 Coordinator of this site? Confirm its status | Pierre-Bénite | France | Unknown status |
| Cabinet médical /ID# 225321 Coordinator of this site? Confirm its status | Reims | France | Unknown status |
| CHU de Rennes - Hospital Sud /ID# 222458 Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
| CH Roanne /ID# 224729 Coordinator of this site? Confirm its status | Roanne | France | Unknown status |
| CH Roubaix - Hopital Victor Provo /ID# 225032 Coordinator of this site? Confirm its status | Roubaix | France | Unknown status |
| Clinique Saint-Hilaire /ID# 223833 Coordinator of this site? Confirm its status | Rouen | France | Unknown status |
| Hôpital Charles-Nicolle /ID# 223589 Coordinator of this site? Confirm its status | Rouen | France | Unknown status |
| Cabinet rhumatologie Dr NECTOUX /ID# 225828 Coordinator of this site? Confirm its status | Sainte-Maxime | France | Unknown status |
| Hôpital d'instruction des armées Bégin /ID# 222440 Coordinator of this site? Confirm its status | Saint-Mandé | France | Unknown status |
| Cabinet Rhumatologie St Michel Sur Orge /ID# 225176 Coordinator of this site? Confirm its status | Saint-Michel-sur-Orge | France | Unknown status |
| CH Saint Nazaire /ID# 225750 Coordinator of this site? Confirm its status | Saint-Nazaire | France | Unknown status |
| Centre Hospitalier Universitaire de Saint Étienne - Hôpital Nord /ID# 222456 Coordinator of this site? Confirm its status | Saint-Priest-en-Jarez | France | Unknown status |
| CHU Strasbourg - Hopital de Hautepierre /ID# 222450 Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
| Groupe Médical Spécialisé - Le Premium /ID# 223719 Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
| CH Bigorre - Site de la Gespe /ID# 225141 Coordinator of this site? Confirm its status | Tarbes | France | Unknown status |
| Cabinet de Rhumatologie Poincare /ID# 224755 Coordinator of this site? Confirm its status | Thionville | France | Unknown status |
| CHU Toulouse - Hopital Purpan /ID# 223150 Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
| University General Hospital of Alexandroupolis /ID# 224880 Coordinator of this site? Confirm its status | Alexandroupoli | Greece | Unknown status |
| General Hospital Asklepieio Voulas /ID# 224131 Coordinator of this site? Confirm its status | Athens | Greece | Unknown status |
| General Hospital of Athens Gennimatas /ID# 225064 Coordinator of this site? Confirm its status | Athens | Greece | Unknown status |
| 251 Airforce General Hospital /ID# 225065 Coordinator of this site? Confirm its status | Athens | Greece | Unknown status |
| General Hospital of Athens Ippokratio /ID# 224164 Coordinator of this site? Confirm its status | Athens | Greece | Unknown status |
| Naval Hospital of Athens /ID# 224135 Coordinator of this site? Confirm its status | Athens | Greece | Unknown status |
| University General Hospital Attikon /ID# 224136 Coordinator of this site? Confirm its status | Athens | Greece | Unknown status |
| University General Hospital of Heraklion PA.G.N.I /ID# 224133 Coordinator of this site? Confirm its status | Heraklion | Greece | Unknown status |
| Olympion General Clinic /ID# 224130 Coordinator of this site? Confirm its status | Pátrai | Greece | Unknown status |
| General Hospital of Patras Agios Andreas /ID# 224132 Coordinator of this site? Confirm its status | Pátrai | Greece | Unknown status |
| Euromedica General Clinic /ID# 224134 Coordinator of this site? Confirm its status | Thessaloniki | Greece | Unknown status |
| Bioclinic Thessaloniki /ID# 224879 Coordinator of this site? Confirm its status | Thessaloniki | Greece | Unknown status |
| General Hospital of Thessaloniki Hippokrateio /ID# 229965 Coordinator of this site? Confirm its status | Thessaloniki | Greece | Unknown status |
| Hermitage Medical Clinic /ID# 239556 Coordinator of this site? Confirm its status | Dublin | Ireland | Unknown status |
| St James Hospital /ID# 224201 Coordinator of this site? Confirm its status | Dublin | Ireland | Unknown status |
| St Vincent's University Hospital /ID# 224200 Coordinator of this site? Confirm its status | Elm Park | Ireland | Unknown status |
| Tallaght University Hospital /ID# 231260 Coordinator of this site? Confirm its status | Tallaght | Ireland | Unknown status |
| HaEmek Medical Center /ID# 222138 Coordinator of this site? Confirm its status | Afula | Israel | Unknown status |
| Hillel Yaffe Medical Center /ID# 222170 Coordinator of this site? Confirm its status | Hadera | Israel | Unknown status |
| Rabin Medical Center /ID# 222694 Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| Rambam Health Care Campus /ID# 222118 Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| The Lady Davis Carmel Medical Center /ID# 223851 Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| Meir Medical Center /ID# 222116 Coordinator of this site? Confirm its status | Kfar Saba | Israel | Unknown status |
| Galilee Medical Center /ID# 222113 Coordinator of this site? Confirm its status | Nahariya | Israel | Unknown status |
| The Chaim Sheba Medical Center /ID# 222034 Coordinator of this site? Confirm its status | Ramat Gan | Israel | Unknown status |
| Tel Aviv Sourasky Medical Center /ID# 222117 Coordinator of this site? Confirm its status | Tel Aviv | Israel | Unknown status |
| Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo /ID# 228889 Coordinator of this site? Confirm its status | Alessandria | Italy | Unknown status |
| ASL 3 Genovese - Ospedale la Colletta /ID# 228892 Coordinator of this site? Confirm its status | Arenzano | Italy | Unknown status |
| Azienda Ospedaliera Universitaria Consorziale Policlinico /ID# 228580 Coordinator of this site? Confirm its status | Bari | Italy | Unknown status |
| Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni /ID# 228967 Coordinator of this site? Confirm its status | Bergamo | Italy | Unknown status |
| ASST Spedali civili di Brescia /ID# 228970 Coordinator of this site? Confirm its status | Brescia | Italy | Unknown status |
| Ospedale Ss. Annunziata /ID# 228809 Coordinator of this site? Confirm its status | Chieti | Italy | Unknown status |
| Azienda Ospedaliero Universitaria di Ferrara - Ospedale Sant'Anna /ID# 228788 Coordinator of this site? Confirm its status | Cona | Italy | Unknown status |
| ASST Gaetano Pini/Presidio Ospedaliero Pini /ID# 228556 Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| ASST Grande Ospedale Metropolitano Niguarda /ID# 228807 Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| Ospedale San Raffaele IRCCS /ID# 229059 Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| Azienda Ospedaliero-Universitaria di Modena /ID# 228554 Coordinator of this site? Confirm its status | Modena | Italy | Unknown status |
| AOU Universita degli Studi della Campania Luigi Vanvitelli /ID# 229057 Coordinator of this site? Confirm its status | Naples | Italy | Unknown status |
| Ospedale San Giovanni Bosco /ID# 228552 Coordinator of this site? Confirm its status | Naples | Italy | Unknown status |
| Azienda Ospedaliera Universitaria Paolo Giaccone /ID# 228160 Coordinator of this site? Confirm its status | Palermo | Italy | Unknown status |
| Azienda Ospedaliera Civico Di Cristina Benfratelli- P.O. Civico /ID# 228912 Coordinator of this site? Confirm its status | Palermo | Italy | Unknown status |
| Fondazione IRCCS Policlinico /ID# 227937 Coordinator of this site? Confirm its status | Pavia | Italy | Unknown status |
| Azienda Ospedaliero Universitaria Pisana /ID# 228550 Coordinator of this site? Confirm its status | Pisa | Italy | Unknown status |
| Azienda Ospedaliera Regionale San Carlo /ID# 228648 Coordinator of this site? Confirm its status | Potenza | Italy | Unknown status |
| Fondazione Policlinico Universitario Campus Bio-Medico di Roma /ID# 229063 Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
| Sapienza University /ID# 228014 Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
| Azienda Ospedaliero-Universitaria Sant'Andrea /ID# 227942 Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 229061 Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
| Istituto Clinico Humanitas /ID# 227943 Coordinator of this site? Confirm its status | Rozzano | Italy | Unknown status |
| Azienda Ospedaliera Universitaria "San Giovanni di Dio e Ruggi d'Aragona /ID# 229065 Coordinator of this site? Confirm its status | Salerno | Italy | Unknown status |
| Azienda Ospedaliero-Universitaria Senese-Ospedale Santa Maria delle Scotte /ID# 227938 Coordinator of this site? Confirm its status | Siena | Italy | Unknown status |
| Azienda Ospedaliero Universitaria Ospedali Riuniti Do Ancona /ID# 229440 Coordinator of this site? Confirm its status | Torette | Italy | Unknown status |
| Ospedale Mauriziano di Torino /ID# 228888 Coordinator of this site? Confirm its status | Turin | Italy | Unknown status |
| Azienda Ospedaliera Universitaria Friuli Centrale/Presidio Ospedaliero Universit /ID# 228551 Coordinator of this site? Confirm its status | Udine | Italy | Unknown status |
| Azienda Ospedaliera Universitaria di Verona/Ospedale Borgo Trento /ID# 228553 Coordinator of this site? Confirm its status | Verona | Italy | Unknown status |
| Mubarak Hospital /ID# 224139 Coordinator of this site? Confirm its status | Hawalli | Kuwait | Unknown status |
| KOC Hospital /ID# 224138 Coordinator of this site? Confirm its status | Kuwait City | Kuwait | Unknown status |
| Ameeri Hospital /ID# 224140 Coordinator of this site? Confirm its status | Kuwait City | Kuwait | Unknown status |
| Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 224361 Coordinator of this site? Confirm its status | Guadalajara | Mexico | Unknown status |
| Private Office Dr. Orozco /ID# 243257 Coordinator of this site? Confirm its status | Guadalajara | Mexico | Unknown status |
| Centro de Estudios de Investigación Básica y Clínica, S.C. /ID# 224364 Coordinator of this site? Confirm its status | Guadalajara | Mexico | Unknown status |
| Centro Integral en Reumatologia S.A de C.V /ID# 224363 Coordinator of this site? Confirm its status | Guadalajara | Mexico | Unknown status |
| Centro Especializado en Diabetes, Obesidad y Prevencion de Enfermedades Cardiova /ID# 224360 Coordinator of this site? Confirm its status | Mexico City | Mexico | Unknown status |
| RM Pharma Specialists S.A de C.V. /ID# 224359 Coordinator of this site? Confirm its status | Mexico City | Mexico | Unknown status |
| CINTRE, Centro de Investigación y Tratamiento Reumatológico SC /ID# 240836 Coordinator of this site? Confirm its status | Mexico City | Mexico | Unknown status |
| Consultorio Medico Privado - Miryam Eguia Bernal /Id# 243255 Coordinator of this site? Confirm its status | Monterrey | Mexico | Unknown status |
| Consultorio Privado Jorge Rojas Serrano /Id# 243258 Coordinator of this site? Confirm its status | Puebla City | Mexico | Unknown status |
| District clinical hospital /ID# 227662 Coordinator of this site? Confirm its status | Khanty-Mansyisk | Russia | Unknown status |
| Moscow Regional Research and Clinical Institute n.a. Vladimirskiy (MONIKI) /ID# 224852 Coordinator of this site? Confirm its status | Moscow | Russia | Unknown status |
| City Clinical Hospital #52 /ID# 242947 Coordinator of this site? Confirm its status | Moscow | Russia | Unknown status |
| Omsk Regional Clinic Hospital /ID# 232029 Coordinator of this site? Confirm its status | Omsk | Russia | Unknown status |
| Orenburg State Medical University /ID# 243615 Coordinator of this site? Confirm its status | Orenburg | Russia | Unknown status |
| Republican hospital named after V.A. Baranov /ID# 227661 Coordinator of this site? Confirm its status | Petrozavodsk | Russia | Unknown status |
| Nort-Western State Medical University n.a. Mechnikov /ID# 223419 Coordinator of this site? Confirm its status | Saint Petersburg | Russia | Unknown status |
| Clinical Rheumatologic Hospital No 25 /ID# 242475 Coordinator of this site? Confirm its status | Saint Petersburg | Russia | Unknown status |
| Military Medical Academy n.a. Kirov /ID# 242351 Coordinator of this site? Confirm its status | Saint Petersburg | Russia | Unknown status |
| Clinic of Samara State Medical University /ID# 241168 Coordinator of this site? Confirm its status | Samara | Russia | Unknown status |
| Samara Regional Clinical Hospital n.a. V. D. Seredavin /ID# 227852 Coordinator of this site? Confirm its status | Samara | Russia | Unknown status |
| Budgetary Institution of the Khanty-Mansiysk Autonomous Okrug-Yugra Surgut Dist /ID# 243313 Coordinator of this site? Confirm its status | Surgut | Russia | Unknown status |
| LLC MC RevmaMed /ID# 239162 Coordinator of this site? Confirm its status | Syktyvkar | Russia | Unknown status |
| Nebbiolo Clinical Research Center /ID# 224900 Coordinator of this site? Confirm its status | Tomsk | Russia | Unknown status |
| GBUZ TO Regional Clinical Hospital No. 1 /ID# 241113 Coordinator of this site? Confirm its status | Tyumen | Russia | Unknown status |
| Ulyanovsk Regional Clinical Hospital /ID# 239164 Coordinator of this site? Confirm its status | Ulyanovsk | Russia | Unknown status |
| Voronezh State Medical Univers /ID# 224854 Coordinator of this site? Confirm its status | Voronezh | Russia | Unknown status |
| Yaroslavl State Medicat University /ID# 224851 Coordinator of this site? Confirm its status | Yaroslavl | Russia | Unknown status |
| International Medical Center /ID# 243235 Coordinator of this site? Confirm its status | Jeddah | Saudi Arabia | Unknown status |
| King Abdulaziz University Hospital /ID# 222724 Coordinator of this site? Confirm its status | Jeddah | Saudi Arabia | Unknown status |
| Saudi German Hospital Jeddah /ID# 243234 Coordinator of this site? Confirm its status | Jeddah | Saudi Arabia | Unknown status |
| Saudi German Hospital /ID# 224137 Coordinator of this site? Confirm its status | Mushait | Saudi Arabia | Unknown status |
| King Fahad Medical City /ID# 222917 Coordinator of this site? Confirm its status | Riyadh | Saudi Arabia | Unknown status |
| Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 241052 Coordinator of this site? Confirm its status | Kaohsiung City | Taiwan | Unknown status |
| China Medical University Hospital /ID# 241051 Coordinator of this site? Confirm its status | Taichung | Taiwan | Unknown status |
| Chi-Mei Medical Center /ID# 241745 Coordinator of this site? Confirm its status | Tainan | Taiwan | Unknown status |
| Tri-Service General Hospital /ID# 241746 Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
| National Taiwan University Hospital /ID# 241050 Coordinator of this site? Confirm its status | Taipei City | Taiwan | Unknown status |
| Linkou Chang Gung Memorial Hospital /ID# 241053 Coordinator of this site? Confirm its status | Taoyuan City | Taiwan | Unknown status |
| Asociacion Española /ID# 222009 Coordinator of this site? Confirm its status | Montevideo | Uruguay | Unknown status |
| Medica Uruguaya /ID# 222008 Coordinator of this site? Confirm its status | Montevideo | Uruguay | Unknown status |
Related publications
- Achievement and Maintenance of Remission with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in Italy: 1-Year Data from UPHOLD, a Prospective Real-World Observational Study.Rheumatol Ther · 2026 · PMID 41968259
- Achievement and Maintenance of Disease Targets with Upadacitinib in Rheumatoid Arthritis: 2-Year Outcomes from the UPHOLD Real-World Study.Rheumatol Ther · 2026 · PMID 41854829
- Sleep improvement in patients with rheumatoid arthritis treated with upadacitinib in real-world practice: results from the SLEERA study.Arthritis Res Ther · 2026 · PMID 41761286
This page is information, not medical advice. Discuss any trial with your doctor.