NCT04502225Recruiting
Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
Impact of Decreased Venous Return on Supine Blood Pressure
Source: ClinicalTrials.gov · Last updated 22 Oct 2026
Brief summary (registry, in English)
Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 44 (estimated)
- First submitted
- 20 Jul 2020
- Start date
- 21 Aug 2020
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- Vanderbilt University Medical Center
- Diseases
- High blood pressure
- NCT number
- NCT04502225
What you commit to
- Study type: Interventional
- Planned participants: 44
- From 21 Aug 2020 to the primary completion date, 31 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- High-risk patients (for example: heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction)
- History of serious allergies or asthma.
Other
- All medical students
- Pregnant women
Who the study is looking for
- Patients with autonomic failure and with supine hypertension from all races
- Males and females, between 18 to 85 years
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.