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NCT04504526RecruitingEarly phase 1

Value of Chemokine Receptor CXCR4 Imaging for Diagnosis and Prognostic Evaluation in Lymphoproliferative Diseases

Value of Chemokine Receptor CXCR4-targeting Molecular Imaging for Diagnosis and Prognostic Evaluation in Lymphoproliferative Diseases

Source: ClinicalTrials.gov · Last updated 21 Jul 2026

Brief summary (registry, in English)

Chemokine receptor CXCR4 is normally expressed on T-lymphocytes, B-lymphocytes, monocytes, macrophages, neutrophils and eosinophils as well as hematopoietic stem and progenitor cells (HSPC) in the bone marrow. 68Ga-Pentixafor PET/CT represents a promising method for the in vivo assessment of the CXCR4 expression status in cancer patients, especially in hematologic malignancies. This prospective study is going to investigate whether metabolic characterization by 68Ga-Pentixafor PET/CT may be superior for diagnosis, risk stratification, and the prognostic evaluation in lymphoproliferative diseases.

Status (registry)
Recruiting
Phase (registry)
Early phase 1
Study type
Interventional
Enrollment
50 (estimated)
First submitted
1 Aug 2020
Start date
7 Aug 2020
Primary completion date
Dec 2027
Lead sponsor
First Affiliated Hospital of Fujian Medical University
NCT number
NCT04504526

What you commit to

  • Study type: Interventional · Early phase 1
  • Planned participants: 50
  • From 7 Aug 2020 to the primary completion date, Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • known allergy against Pentixafor

Other

  • pregnancy
  • breastfeeding

Who the study is looking for

  • suspected or confirmed untreated Lymphoproliferative diseases patients
  • 18F-FDG PET/CT within two weeks
  • signed written consent.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University
Coordinator of this site? Confirm its status
FuzhouChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.