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NCT04506606Completed

Cardiac Rehab Effects in HFpEF

Efficacy of Exercise Training in Patients With HFpEF

Source: ClinicalTrials.gov · Last updated 6 Oct 2026

Brief summary (registry, in English)

This research in Veterans with heart failure with preserved ejection fraction (HFpEF) will provide new information on the mechanisms determining the patients' exercise intolerance and the efficacy of regular physical activity to improve this shortcoming by alleviating the patients' neurocirculatory abnormalities. Specifically, the investigators will focus on the role of nerves originating in working limb muscles in determining the patients' exercise intolerance and compromised fatigue resistance before and after a chronic exercise intervention. By focusing on a specific mechanism, this project will evaluate the validity of exercise as an alternative treatment strategy with the overall purpose of improving the quality of life of Veterans with HFpEF.

Status (registry)
Completed
Study type
Interventional
Enrollment
45 (actual)
First submitted
6 Aug 2020
Start date
2 May 2022
Primary completion date
30 Sept 2026
Lead sponsor
VA Office of Research and Development
NCT number
NCT04506606

What you commit to

  • Study type: Interventional
  • Participants enrolled: 45
  • From 2 May 2022 to the primary completion date, 30 Sept 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Lab values

  • heart failure with reduced ejection fraction

Who the study is looking for

  • heart failure with preserved ejection fraction

Age in the registry: 21 years to 85 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
VA Salt Lake City Health Care System, Salt Lake City, UT
Coordinator of this site? Confirm its status
Salt Lake CityUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.