NCT04517669Completed
Effectiveness of Treatment With Tofacitinib in Patients With Psoriatic Arthritis in Routine Clinical Practice
A Non-Interventional Multinational Study of Tofacitinib in Patients Treated for Psoriatic Arthritis
Source: ClinicalTrials.gov · Last updated 14 Oct 2025
Brief summary (registry, in English)
This is a Multinational Study of Tofacitinib in Patients Treated for Psoriatic Arthritis in order to evaluate the effectiveness of treatment with tofacitinib on disease activity, remission, and Quality of Life, in a real-world setting over a 12-month observation period
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 116 (actual)
- First submitted
- 14 Aug 2020
- Start date
- 17 May 2021
- Primary completion date
- 30 Jul 2024
- Lead sponsor
- Pfizer
- Diseases
- Psoriasis, Psoriatic arthritis
- NCT number
- NCT04517669
What you commit to
- Study type: Observational
- Participants enrolled: 116
- From 17 May 2021 to the primary completion date, 30 Jul 2024
- 41 sites in 8 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Receipt of any investigational drug within 3 months before study inclusion
- Concomitant treatment with a biological disease-modifying antirheumatic drugs (bDMARD)
Other illness
- Recent herpes zoster infection (within past 6 months) or history of severe disseminated herpes zoster infection
- Active treatment for a malignancy
Other
- Contraindications according to the Xeljanz® (tofacitinib) Prescribing Information
- Patient is pregnant or breastfeeding
Who the study is looking for
- Patients aged ≥ 18 years
- Moderate to severe PsA disease activity diagnosed
- Patients for whom the physician's decision has been made to initiate treatment with tofacitinib, in usual clinical practice conditions and in compliance with the local label
- Patients are treatment naïve to tofacitinib on the date of providing informed consent
- Evidence of a personally signed and dated informed consent document indicating that the patient (or a legally acceptable representative) has been informed of all pertinent aspects of the study
- Patients on DMARDs must have not had a treatment change in the past 3 months
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (41)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Algemeen Stedelijk Ziekenhuis Coordinator of this site? Confirm its status | Aalst | Belgium | Unknown status |
| AZ Sint Jan Coordinator of this site? Confirm its status | Bruges | Belgium | Unknown status |
| Nova Reuma Społka Partnerska Coordinator of this site? Confirm its status | Genk | Belgium | Unknown status |
| Sygehus Vendsyssel Hospital Coordinator of this site? Confirm its status | Hjørring | Denmark | Unknown status |
| Hospital Universitario Puerta del Mar Coordinator of this site? Confirm its status | Cadiz | Spain | Unknown status |
| Hospital de Especialidades de Jerez de la Frontera Coordinator of this site? Confirm its status | Cadiz | Spain | Unknown status |
| Hospital Universitario Reina Sofia Coordinator of this site? Confirm its status | Córdoba | Spain | Unknown status |
| Hospital Universitario San Cecilio Coordinator of this site? Confirm its status | Granada | Spain | Unknown status |
| Hospital Universitario Virgen de las Nieves Coordinator of this site? Confirm its status | Granada | Spain | Unknown status |
| Hospital Regional Universitario de Malaga Coordinator of this site? Confirm its status | Málaga | Spain | Unknown status |
| Hospital Universitario Central De Asturias Coordinator of this site? Confirm its status | Oviedo | Spain | Unknown status |
| Hospital Universitario Virgen Macarena Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
| Hospital Quironsalud Infanta Luisa Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
| C.H. Universitario de Vigo- Hospital Meixoeiro Coordinator of this site? Confirm its status | Vigo | Spain | Unknown status |
| Turku University Hospital Coordinator of this site? Confirm its status | Turku | Finland | Unknown status |
| CHU Besancon - Hopital Jean Minjoz Coordinator of this site? Confirm its status | Besançon | France | Unknown status |
| Centre Hospitalier Jean Rougier Coordinator of this site? Confirm its status | Cahors | France | Unknown status |
| Infirmerie Protestante de Lyon Coordinator of this site? Confirm its status | Caluire-et-Cuire | France | Unknown status |
| CHU Clermont Ferrand - Hôpital Gabriel Montpied Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| Hopital PASTEUR Coordinator of this site? Confirm its status | Nice | France | Unknown status |
| CHR Orléans Coordinator of this site? Confirm its status | Orléans | France | Unknown status |
| Hopital Purpan Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
| CHU Tours - Hôpital Trousseau Coordinator of this site? Confirm its status | Tours | France | Unknown status |
| Barzilai Medical Center Coordinator of this site? Confirm its status | Ashkelon | Israel | Unknown status |
| Soroka University Medical Center Coordinator of this site? Confirm its status | Beersheba | Israel | Unknown status |
| Rambam Health Care Center Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| The Lady Davis Carmel Medical Center Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| Bnai Zion Medical Center Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| Hadassah Hebrew University Medical Center - Ein Kerem Coordinator of this site? Confirm its status | Jerusalem | Israel | Unknown status |
| Hadassah University Hospital - Ein Kerem Coordinator of this site? Confirm its status | Jerusalem | Israel | Unknown status |
| Galilee Medical Center Coordinator of this site? Confirm its status | Nahariya | Israel | Unknown status |
| Sheba medical center Coordinator of this site? Confirm its status | Ramat Gan | Israel | Unknown status |
| Chaim Sheba Medical Center Coordinator of this site? Confirm its status | Ramat Gan | Israel | Unknown status |
| Tel-Aviv Sourasky Medical Center Coordinator of this site? Confirm its status | Tel Aviv | Israel | Unknown status |
| The Baruch Padeh Medical Center, Poriya Coordinator of this site? Confirm its status | Tiberias | Israel | Unknown status |
| Medisch Spectrum Twente, Haaksbergerstraat Coordinator of this site? Confirm its status | Enschede | Netherlands | Unknown status |
| Medisch Centrum Leeuwarden Coordinator of this site? Confirm its status | Leeuwarden | Netherlands | Unknown status |
| Lund University Coordinator of this site? Confirm its status | Lund | Sweden | Unknown status |
| Skånes universitetssjukhus Malmö Coordinator of this site? Confirm its status | Malmö | Sweden | Unknown status |
| Karolinska University Hospital, Solna Coordinator of this site? Confirm its status | Stockholm | Sweden | Unknown status |
| Norrlands University Hospital Umeå, Reumatologiska kliniken Västerbotten Coordinator of this site? Confirm its status | Umeå | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.