NCT04527874Completed
Viral Load Triggered ART Care in Lesotho
Assessment of a Viral Load Result-driven Automated Differentiated Service Delivery Model for Participants Taking Antiretroviral Therapy in Lesotho
Source: ClinicalTrials.gov · Last updated 1 Aug 2025
Brief summary (registry, in English)
This cluster randomized clinical trial at 18 nurse-led rural health centers in Lesotho will test an automated differentiated service delivery model using viral load results, other clinical characteristics and participants' preference to automatically triage participants into groups requiring different levels of attention and care.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 5809 (actual)
- First submitted
- 9 Mar 2020
- Start date
- 14 Oct 2020
- Primary completion date
- 7 Aug 2024
- Lead sponsor
- Swiss Tropical & Public Health Institute
- Diseases
- HIV
- NCT number
- NCT04527874
What you commit to
- Study type: Interventional
- Participants enrolled: 5809
- From 14 Oct 2020 to the primary completion date, 7 Aug 2024
- 18 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- nurse-led public or missionary clinic in the districts of Butha-Buthe and Mokhotlong;
- consent of clinic management (signed agreement with clinic management);
- access to the internet (internet connection must not be constant, but there must be possibility to down- and upload information daily); and
- the clinic sends plasma VL samples to Butha-Buthe government hospital laboratory for analysis.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (18)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Boiketsiso Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| Makhunoane Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| Linakeng Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| Ngoajane Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| Muela Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| Tsime Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| Rampai Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| Motete Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| St Paul Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| St. Peters Health Center Coordinator of this site? Confirm its status | Butha-Buthe | Lesotho | Unknown status |
| St. Martins Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
| Libibing Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
| St. James Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
| Linakaneng health center Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
| Molikaliko health center Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
| Mapholaneng Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
| Moeketsane Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
| Malefiloane health center Coordinator of this site? Confirm its status | Mokhotlong | Lesotho | Unknown status |
Related publications
- Integrating clinical decision support and mobile health for differentiated HIV service delivery in Lesotho (VITAL): a cluster-randomised non-inferiority trial.EClinicalMedicine · 2026 · PMID 42005925
This page is information, not medical advice. Discuss any trial with your doctor.