NCT04532814Active, not recruiting
Exercise-stimulated Muscle Glucose Uptake in Upper Body Obesity
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
The purpose of this study is to provide the first integrated examination of the interaction between muscle insulin action and exercise-stimulated muscle glucose uptake in obesity from the whole body to the cellular/molecular level.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 48 (estimated)
- First submitted
- 27 Aug 2020
- Start date
- 6 Sept 2020
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Mayo Clinic
- Diseases
- Obesity
- NCT number
- NCT04532814
What you commit to
- Study type: Interventional
- Planned participants: 48
- From 6 Sept 2020 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of prior upper abdominal surgery such as adjustable gastric banding, pyloroplasty and vagotomy.
Other illness
- Active systemic illness or malignancy.
- Symptomatic macrovascular or microvascular disease.
Lab values
- Use of glucose-lowering agents.
Age
- Age \< 18 or \> 55 years (premenopausal women and age-matched men).
Other
- For female subjects: positive pregnancy test at the time of enrollment or study
Who the study is looking for
- For the exercise studies of leg glucose uptake - "insulin sensitive" group:
- Sedentary, normal weight, premenopausal women.
- Sedentary, age-matched normal weight men.
- Weight stable for two (2) months prior to study.
- Willing to provide written, informed consent.
- For the exercise studies of leg glucose uptake - "insulin resistant" group:
- For the exercise studies of leg glucose uptake - "insulin resistant" group:
- Upper body obese (UBO) premenopausal women.
- Age-matched upper body obese (UBO) men.
- Weight stable for two (2) months prior to study.
- Willing to provide written, informed consent.
Age in the registry: 18 years to 55 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Rochester Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.