NCT04532970Completed
BAPS in Botswana: The Thotloetso Trial
Testing the Combination of Behavioral Activation and Problem Solving as a Novel Behavioral Smoking Cessation Intervention for Smokers With HIV in Botswana
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
The main purpose of this research study is to compare traditional behavioral smoking cessation therapy with a different type of behavioral therapy-known as behavioral activation problem solving (BAPS)-for smoking cessation. Standard smoking cessation counseling (SC) focuses on self-monitoring, identifying smoking triggers and how to manage them, relaxation and social support for non-smoking, and relapse prevention. BAPS focuses on recognizing he feelings you are having that lead to smoking and how to overcome those feelings and focus on activities that discourage you from smoking and avoid activities that encourage you to smoke. Both counseling types include gathering information about your personal smoking patterns, your likes, dislikes, and other personal characteristics about your lifestyle. Half of participants who enroll in the study will receive standard smoking cessation counseling (SC) and half will receive BAPS counseling. We will compare the rates of quitting smoking across the two groups at the end of treatment (study week 10), and 12 weeks after the end of treatment (study week 26)
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 651 (actual)
- First submitted
- 25 Aug 2020
- Start date
- 6 May 2021
- Primary completion date
- 1 Dec 2025
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Diseases
- HIV
- NCT number
- NCT04532970
What you commit to
- Study type: Interventional
- Participants enrolled: 651
- From 6 May 2021 to the primary completion date, 1 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Cognitive deficits that impair their ability to provide informed consent
- Current untreated and unstable diagnosis of alcohol dependence (if past use and stable for \>30 days, eligible)
- Psychosis
- Use of chewing tobacco, snuff or snus
- Recent , current, or planned use (next 7 months) of nicotine substitutes or smoking cessation treatments
Who the study is looking for
- \>18 years old
- Smoking cigarettes daily for the past 30 days
- HIV+ with HIV viral load of \<1000 copies/mL, obtained within the 6 months prior to enrollment
- Receiving HIV care at Infectious Diseases Care Clinics (IDCCs) in and around Gaborone
- Able to communicate in English OR Setswana and provide written informed consent
- Planning on residing in the geographic area for at least the next 7 months
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Botswana Coordinator of this site? Confirm its status | Gaborone | Botswana | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.