NCT04536272CompletedPhase 3
Reduced Anticoagulation Targets in ECLS (RATE)
Source: ClinicalTrials.gov · Last updated 2 May 2025
Brief summary (registry, in English)
The objective of the RATE-trial is to study if reduced anticoagulation targets during ECLS diminish bleeding complications without an increase in thromboembolic complications or a negative impact on outcome.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 330 (actual)
- First submitted
- 24 Aug 2020
- Start date
- 1 Oct 2020
- Primary completion date
- 7 Mar 2025
- Lead sponsor
- University Medical Center Groningen
- Diseases
- Heart failure
- NCT number
- NCT04536272
- EudraCT number
- 2019-004125-24
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 330
- From 1 Oct 2020 to the primary completion date, 7 Mar 2025
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of heparin induced thrombocytopenia
Other
- Patients in whom the ECMO is only used to bridge a procedure
- Vital indication for robust anticoagulation (e.g. mechanic valve, pulmonary embolism)
Who the study is looking for
- ECMO treatment during the study period in one of the participating centers
- Age above 18 years
- Written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Amsterdam UMC, location AMC Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
| OLVG location East Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
| University Medical Center Groningen Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
| Leids Universitair Medisch Centrum Coordinator of this site? Confirm its status | Leiden | Netherlands | Unknown status |
| Maastricht Universitair Medisch Centrum Coordinator of this site? Confirm its status | Maastricht | Netherlands | Unknown status |
| Radboud UMC Coordinator of this site? Confirm its status | Nijmegen | Netherlands | Unknown status |
| Erasmus MC Coordinator of this site? Confirm its status | Rotterdam | Netherlands | Unknown status |
| Isala Clinics Coordinator of this site? Confirm its status | Zwolle | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.