NCT04548830CompletedPhase 2
Safety of Lung Cryobiopsy in People With Cancer
Safety of Transbronchial Cryobiopsy in a Cancer Population
Source: ClinicalTrials.gov · Last updated 1 Jul 2026
Brief summary (registry, in English)
The purpose of this study is to find out whether a biopsy technique called transbronchial cryobiopsy (TBCB) is a safe alternative to the standard biopsy procedure (transbronchial forceps biopsy; TBFB). The study researchers think that TBCB may provide better biopsy samples to help diagnose lung disease.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 115 (actual)
- First submitted
- 8 Sept 2020
- Start date
- 8 Sept 2020
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Diseases
- Lung cancer
- NCT number
- NCT04548830
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 115
- From 8 Sept 2020 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Antiplatelet therapy that cannot be held for more than 5 days.
Other illness
- Known pulmonary hypertension or echocardiographic pulmonary artery systolic pressure \>50mmHg
Lab values
- Uncorrectable coagulopathy defined as:
- Platelet count \<50,000 x 10\^9/L or
- prothrombin time international normalized ratio \>1.5
Other
- Patients with pulse oximetry less than 92% on oxygen delivery up to 2 L nasal cannula.
- A secure diagnosis based on clinical and high-resolution CT scan data.
- Any patient deemed unfit to undergo bronchoscopy by the proceduralist
- Female patients with a positive pregnancy test within 30 days of the planned study procedure
Who the study is looking for
- 18 years of age or greater
- Patients with known or suspected diagnosis of cancer and indeterminant pulmonary nodules or diffuse parenchymal lung disease with non-diagnostic clinical profiles for whom a lung biopsy is deemed useful for diagnosis.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) Coordinator of this site? Confirm its status | New York | United States | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.