NCT04553185Completed
Aquaporin-4 Single Nucleotide Polymorphisms in Patients With Idiopathic and Familial Parkinson's Disease
Study on the Effects of Single Nucleotide Polymorphisms in Aquaporin-4 (AQP4) Gene on the Clinical Phenotype in Patients With Idiopathic and Familial Parkinson's Disease.
Source: ClinicalTrials.gov · Last updated 18 May 2026
Brief summary (registry, in English)
The purpose of this study is to understand the relationship between problems in sleep, genetic variations in the Aquaporin-4 gene (AQP4), and the development of Parkinson's Disease.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 733 (actual)
- First submitted
- 26 Aug 2020
- Start date
- 28 Nov 2018
- Primary completion date
- 30 Apr 2026
- Lead sponsor
- University of Exeter
- Diseases
- Parkinson disease
- NCT number
- NCT04553185
What you commit to
- Study type: Observational
- Participants enrolled: 733
- From 28 Nov 2018 to the primary completion date, 30 Apr 2026
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of other neurological disorders and known intracranial co-morbidities such as stroke, haemorrhage, space-occupying lesions
Other
- Inability to perform online neuropsychological assessment
- Inability to have access to informatics technology to perform the online assessment tests
- Inability to travel for the assessments
- Native language different from English
Who the study is looking for
- 18-85 years of age
- Able to give informed consent
- Able to perform online neuropsychological examinations
- Diagnosis of PD according to Brain Bank Criteria
- No presence or personal or family history of other neurological or psychiatric disorders
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| East Kent University Hospitals NHS Foundation Trust Coordinator of this site? Confirm its status | Ashford | United Kingdom | Unknown status |
| University Of Exeter Coordinator of this site? Confirm its status | Exeter | United Kingdom | Unknown status |
| Prince Phillip Hospital Coordinator of this site? Confirm its status | Llanelli | United Kingdom | Unknown status |
| Lewisham and Greenwich NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.