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NCT04554277Terminated

Medico-economic Evaluation of Therapeutic Adaptation Guided by the Soluble Suppression of Tumorigenicity 2 (sST-2) Biomarker in the Management of Patients With Acute Heart Failure

Source: ClinicalTrials.gov · Last updated 24 Sept 2026

Brief summary (registry, in English)

Management of patients with heart Failure remains a major health concern because of the high rate of rehospitalization, mortality and induced-cost. Biomarkers could help to guide the management of patients with heart failure (HF). Soluble suppression of tumorigenicity 2 (sST2) appears as a promising biomarker. As a working hypothesis, we postulate that sST2 values monitoring could be an helpful guide for medical management in an attempt to reduce hospital readmission.

Status (registry)
Terminated
Study type
Interventional
Enrollment
154 (actual)
First submitted
14 Sept 2020
Start date
27 Apr 2021
Primary completion date
14 Apr 2026
Lead sponsor
University Hospital, Montpellier
NCT number
NCT04554277

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Scheduled valve surgery

Other illness

  • Waiting for heart transplantation

Other

  • No fluent french
  • Not able to provide informed consent
  • Hemodynamic instability
  • Poor outcome during the first week.
  • Pregnancy
  • Participating to other study

Who the study is looking for

  • 18 years or older
  • Hospitalization for heart failure (NTproBNP(N-terminal pro-Brain Natriuretic Peptid) ≥450 pg/ml (ou BNP ≥400 pg/ml)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (12)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
CHU AngersAngersFranceUnknown status
CHU BesançonBesançonFranceUnknown status
CH BeziersBéziersFranceUnknown status
CHU CaenCaenFranceUnknown status
Chu GrenobleGrenobleFranceUnknown status
Arnaud de Villeneuve HospitalMontpellierFranceUnknown status
Lapeyronie HospitalMontpellierFranceUnknown status
CHU NîmesNîmesFranceUnknown status
APHP PompidouParisFranceUnknown status
CHU RennesRennesFranceUnknown status
CHU ToulouseToulouseFranceUnknown status
CHU VannesVannesFranceUnknown status

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This page is information, not medical advice. Discuss any trial with your doctor.