Sign in

NCT04563650Active, not recruiting

COVID-19 Serology and Immunosenescence

Kinetics of COVID-19-neutralising Antibodies in Patients Residing in EHPAD / USLD: Influence of Immunosenescence

Source: ClinicalTrials.gov · Last updated 15 Jun 2026

Brief summary (registry, in English)

This study aims to determine how long COVID-19 neutralizing antibodies can be detected in an elderly institutionalized population presenting fragility factors. This study also aims to stratify seroconversion by immunological profiles of the elderly patients residing in the EHPAD. This stratification requires the measurement of immunological marker levels already described in immunosenescence and also involved in the development of certain chronic infectious diseases more common in the elderly population. This analysis will enable the investigators to describe an immunological, clinical and biological profile representing a patient who has developed an immunity against COVID 19. It will also help the investigators to understand the different mechanisms leading to a reduced immune response after a potential administration of a vaccine. Finally, it will help describe the immune profiles of elderly residents who presented with non-severe forms of COVID-19.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
98 (actual)
First submitted
18 Sept 2020
Start date
29 Aug 2020
Primary completion date
12 Mar 2021
Lead sponsor
Centre Hospitalier Universitaire, Amiens
NCT number
NCT04563650

What you commit to

  • Study type: Interventional
  • Participants enrolled: 98
  • From 29 Aug 2020 to the primary completion date, 12 Mar 2021
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • The patient or his legal representative refused to participate in the study
  • Heavily sedated patients

Who the study is looking for

  • Residents of the EHPAD/USLD St Victor of the Amiens CHU who took part in the screening campaign (RT-PCR and serology) organized by the Amiens CHU
  • residents who signed a consent form to participate in the study

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
CHU Amiens
Coordinator of this site? Confirm its status
AmiensFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.