NCT04563741Completed
MOVE!+UP: Testing a Tailored Weight Management Program for Veterans With PTSD
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
Posttraumatic Stress Disorder (PTSD) is common among Veterans and results in poor psychological functioning, quality of life, and physical health. This includes having disproportionately high rates of obesity, in part due to PTSD symptoms interfering with physical activity and healthy diet. Unfortunately, Veterans with PTSD have poorer weight loss outcomes than those without PTSD in VA's existing weight management program, MOVE!. Based on pilot work, it appears that a weight management program that augments standard PTSD care and targets PTSD-related barriers to weight loss improves weight and PTSD symptoms. Whether it improves these issues more than standard VA care is in need of study, which is the focus of the proposed research. The proposed study also seeks to understand factors that would interfere with and facilitate implementing the program in VA if it is effective. This Veteran-centered, tailored weight loss program may efficiently benefit both physical and mental health of Veterans with PTSD, addressing standard care limitations.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 174 (actual)
- First submitted
- 8 Sept 2020
- Start date
- 1 Oct 2020
- Primary completion date
- 26 Mar 2025
- Lead sponsor
- VA Office of Research and Development
- Diseases
- Obesity
- NCT number
- NCT04563741
What you commit to
- Study type: Interventional
- Participants enrolled: 174
- From 1 Oct 2020 to the primary completion date, 26 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Based on clinical judgment, would be unable to participate because of:
- acutely exacerbated substance use, mental health, or chronic medical conditions
- or moderate to severe chronic, progressive neurologic conditions such as Dementia
- had bariatric surgery within the last 12 months or plan to undergo bariatric surgery within the next 6 months.
- Report they cannot safely weigh themselves using the mailed study scale due to mobility issues or use of assistive devices
- Baseline weight \>440 lbs
Other
- Not fluent in English, severe hearing loss, no phone access
- Current MOVE! participation
- Current pregnancy
Who the study is looking for
- PTSD Diagnosis: standard criteria for PTSD Checklist for DSM-5 (PCL-5): lifetime experience of trauma and a score of 33
- Overweight or obesity based on Body Mass Index (BMI) of 25 kg/m2
- Primary Care Provider or other physician approval
- Willing to participate in all intervention or control and assessment activities
- Enrolled in PTSD treatment
- Must have active VA Puget Sound Health Care System medical record.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| VA Puget Sound Health Care System Seattle Division, Seattle, WA Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
Related publications
- Enhanced Weight Management Program for Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial.JAMA Netw Open · 2026 · PMID 41893847
This page is information, not medical advice. Discuss any trial with your doctor.