NCT04566341Enrolling by invitation
Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 22 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this research is to determine (1) the feasibility of tethered capsule OCT esophageal imaging in the Parkinson's Disease population; (2) the morphologic changes in the enteric nervous system of the esophagus in patients with Parkinson's disease.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 20 (estimated)
- First submitted
- 11 Aug 2020
- Start date
- 4 May 2019
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Parkinson disease
- NCT number
- NCT04566341
What you commit to
- Study type: Observational
- Planned participants: 20
- From 4 May 2019 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent intestinal resection (within the last six months)
- Prior gastric, esophageal or oropharyngeal surgery
Other illness
- Atypical or secondary Parkinson Disease
- Esophageal fistula and/or esophageal strictures with a luminal stricture diameter that is smaller than the diameter of the capsule
Other
- Inability to swallow capsules
- Pregnancy, according to participant information
Who the study is looking for
- Idiopathic Parkinson's disease as defined by the United Kingdom PD Society Brain Bank Criteria
- Parkinson Disease Hoehn and Yahr stage 2-4
- Participants on stable dose of Parkinson Disease medications for at least 4 weeks prior to the study screening
- Participants between 40 and 85 years old
- Participants who are capable of giving informed consent
Age in the registry: 40 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.