NCT04569773Active, not recruiting
Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer
Preservation of Ovaries in Endometrial Malignancies: GYN POEM Trial
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to learn more about the factors that influence decision-making before surgery (distress about cancer and/or reproductive concerns) and the possibility of regret after surgery.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 43 (actual)
- First submitted
- 24 Sept 2020
- Start date
- 23 Sept 2020
- Primary completion date
- 23 Sept 2027
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Diseases
- Endometrial cancer, Ovarian cancer
- NCT number
- NCT04569773
What you commit to
- Study type: Observational
- Participants enrolled: 43
- From 23 Sept 2020 to the primary completion date, 23 Sept 2027
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior bilateral oophorectomy
- Women currently on hormonal contraception, letrozole, or tamoxifen may not opt-in to AMH
- Women who completed chemotherapy within \<12 months may not opt-in to AMH
Other illness
- Known Lynch syndrome
- Personal history of hormone receptor-positive breast carcinoma
- Increased risk of ovarian cancer identified on the basis of family or personal history
- Women who have pituitary dysfunction (or any pituitary disorders) may not opt-in to AMH
Other
- Women who recently underwent ovarian stimulation within the past 3 months may not opt-in to AMH
Who the study is looking for
- Women aged ≥ 18 and ≤ 50 years
- Premenopausal
- Endometrioid histological diagnosis
- Scheduled for surgical intervention at MSKCC
- FIGO grade 1-2, clinical stage I
- Disease confined to uterus, no clear evidence of deep (≥50%) myoinvasion on imaging (MRI preferred, ultrasound optional)
- Normal ovaries on preoperative imaging
- Able to provide informed consent
- English-speaking
Age in the registry: 18 years to 50 years · Sex: Female · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Memorial Sloan Kettering Basking Ridge (All Protocol Activities) Coordinator of this site? Confirm its status | Basking Ridge | United States | Unknown status |
| Memorial Sloan Kettering Cancer Center @ Suffolk (All protocol activities) Coordinator of this site? Confirm its status | Commack | United States | Unknown status |
| Memorial Sloan Kettering Westchester (All Protocol Activities) Coordinator of this site? Confirm its status | Harrison | United States | Unknown status |
| Hartford Healthcare (Data Collection) Coordinator of this site? Confirm its status | Hartford | United States | Unknown status |
| Memorial Sloan Kettering Monmouth (All Protocol Activities) Coordinator of this site? Confirm its status | Middletown | United States | Unknown status |
| Memorial Sloan Kettering Bergen (All Protocol Activities) Coordinator of this site? Confirm its status | Montvale | United States | Unknown status |
| Memorial Sloan Kettering Cancer Center (All Study Activities) Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Memorial Sloan Kettering Nassau (All Protocol Activities) Coordinator of this site? Confirm its status | Rockville Centre | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.