NCT04570735Completed
MRI Biomarkers in Diabetic Kidney Disease
Source: ClinicalTrials.gov · Last updated 17 Dec 2024
Brief summary (registry, in English)
Diabetic kidney disease is one of the most severe and frequent complications of diabetes. Few preclinical markers are available apart from plasma creatinine and microalbuminuria. These markers are imperfect (some patients with advanced renal disease do not have an increase in markers) and late. Therefor there is an uncovered need to identify complementary biomarkers. Magnetic Resonance Spectroscopy (MRS) is a Magnetic Resonance Imaging (MRI) technique that allows the physiology and biochemistry of human body tissues to be studied in a non-invasive and non-irradiating manner.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 30 (actual)
- First submitted
- 18 Sept 2020
- Start date
- 7 Oct 2020
- Primary completion date
- 26 Jan 2024
- Lead sponsor
- Poitiers University Hospital
- Diseases
- Chronic kidney disease, Obesity
- NCT number
- NCT04570735
What you commit to
- Study type: Observational
- Participants enrolled: 30
- From 7 Oct 2020 to the primary completion date, 26 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \< 35 years History of kidney transplant Any contraindication to an MRI examination Legal protection, namely minors, persons deprived of their liberty by a judicial or administrative decision, persons residing in a health or social establishment, adults under legal protection and finally patients in emergency situations Pregnant or lactating women, women of childbearing age who do not have effective contraception
Who the study is looking for
- Common to all 3 category
- Male or female,
- Age≥ 35 years,
- Subject free, with legal protection guardianship or curatorship;
- Enrollment in the French Social Security system;
- Informed consent signed by the patient
- Obese patients
- BMI \>30 kgm² ;
- With no known diabetes;
- estimated glomerular filtration rate (eGFR) \> 60 ml/min/1.73m² and urine albumin-creatinin ratio (ACR) \< 3 mg/g
- Type 2 diabetic patients without kidney disease
- \- eGFR \> 60 ml/min/1.73m² AND ACR \< 3 mg/g,
- Type 2 diabetic patients with diabetic kidney disease defined as eGFR 30 to 60 ml/min/1.73m² OR ACR \> 30 mg/mmol.
Age in the registry: 35 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Poitiers Coordinator of this site? Confirm its status | Poitiers | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.