NCT04573751Completed
The EPIVER Randomized Controlled Trial
Intracoronary Administration of Epinephrine and Verapamil in the Refractory No-reflow Phenomenon in Patients With Acute Myocardial Infarction: The EPIVER Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 24 Jun 2026
Brief summary (registry, in English)
The trial aims to estimate the efficacy and safety of the intracoronary administration of adrenalin, verapamil, as well as their combination compared to standard treatment in patients with STEMI and refractory coronary no-reflow despite conventional treatment during percutaneous coronary intervention (PPCI)
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 104 (actual)
- First submitted
- 28 Sept 2020
- Start date
- 30 Dec 2020
- Primary completion date
- 31 Jan 2023
- Lead sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
- Diseases
- Coronary artery disease
- NCT number
- NCT04573751
What you commit to
- Study type: Interventional
- Participants enrolled: 104
- From 30 Dec 2020 to the primary completion date, 31 Jan 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Unable to undergo or contra-indications for MRI or SPECT
Who the study is looking for
- patients with ST-elevation myocardial infarction
- Infarct-related artery TIMI flow grade 0-2 during the interventional procedure after the initial opening of the vessel.
- Written the informed consent to participate in research
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cardiology Research Institute, Tomsk NRMC Coordinator of this site? Confirm its status | Tomsk | Russia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.