NCT04578301Recruiting
Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease
Source: ClinicalTrials.gov · Last updated 18 May 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Prospective, observational study to define precipitants and predictors of development of Acute-on-Chronic Liver Failure (ACLF) after surgical interventions, allowing to develop a risk stratification for elective procedures in cirrhotic patients. As well as identifying molecular mechanisms of post-interventional ACLF and thus preparing the ground for development of new therapeutic approaches.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 22 Sept 2020
- Start date
- 22 Sept 2020
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- University Hospital, Bonn
- Diseases
- High blood pressure
- NCT number
- NCT04578301
What you commit to
- Study type: Observational
- Planned participants: 200
- From 22 Sept 2020 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous liver or other transplantation
Other illness
- Patients undergoing surgery as form of palliative cancer therapy
- Presence or history of severe extra-hepatic diseases
- HIV-positive patients
- Patients with acute or subacute liver failure without underlying cirrhosis
Other
- Pregnant or lactating females
- Patients who decline to participate
- Physician´s denial (e.g. the investigator considers that the patient will not follow the protocol scheduled)
Who the study is looking for
- Male or female adult (≥18 years) patient
- With or without liver cirrhosis (diagnosed either histologically or by a combination of clinical, laboratory and radiological signs)
- Or Non-cirrhotic portal hypertension
- Non-pregnant, non-lactating females
- Ability to understand the patient information and to personally sign and date the informed consent to participate in the study
- The patient is co-operative and available for the entire study
- Provided written informed consent
- Indication for surgical intervention
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Bonn Coordinator of this site? Confirm its status | Bonn | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.