NCT04583787Completed
xSPECT-based Myocardial Perfusion Scintigraphy: Consistency of Functional Values and Feasibility of Myocardial Uptake Quantitation in Patients With Suspected Coronary Artery Disease
xSPECT-based Myocardial Perfusion Scintigraphy: Consistency of Functional Values and Feasibility of Myocardial Uptake Quantitation in Patients With Suspected Coronary Artery Disease (xSPECT MPI Study)
Source: ClinicalTrials.gov · Last updated 28 Jun 2024
Brief summary (registry, in English)
This study is to evaluate the feasibility of myocardial Standardized Uptake Volume (SUV) assessment by means of X- (Single photon emission tomography) SPECT/Computed tomography (CT), to assess normal reference value under rest and stress in a homogeneous population without Coronary Artery Disease (CAD) and to assess the variation of absolute quantitative SUV measurements under rest and stress. The values will be evaluated in comparison with perfusion Positron Emission Tomography (PET)/CT (using 82Rb as perfusion tracer) and CT coronary angiography (CTCA) with contrast medium.).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 52 (actual)
- First submitted
- 28 Sept 2020
- Start date
- 7 Dec 2021
- Primary completion date
- 28 May 2024
- Lead sponsor
- University Hospital, Basel, Switzerland
- Diseases
- Coronary artery disease
- NCT number
- NCT04583787
What you commit to
- Study type: Interventional
- Participants enrolled: 52
- From 7 Dec 2021 to the primary completion date, 28 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous history of coronary revascularization
- Participation in another study with investigational drug within the 30 days preceding and during the present study,
- Enrolment into another study using ionizing radiation within the previous 12 months.
Other illness
- Allergy against adenosine
- Allergy against iodinated contrast medium
- Recent myocardial infarction (\<1 month)
- Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
Lab values
- Acute or chronic renal impairment defined as Serum-Creatinine: above 1.5x upper limit of normal (ULN) and/or glomerular filtration rate (GFR) \< 30 ml/min
Other
- Pregnancy
- Severe asthma
- Thyroid hyperfunction
- atrioventricular block (AV) Block \> I grade
- Arrhythmic cardiopathy
- Weight \>101 Kg.
- Enrolment of the investigator, his/her family members, employees and other dependent persons,
- Claustrophobia
- Intake of caffeine \<24 Hours before the first day of examination
Who the study is looking for
- Referral to non-invasive nuclear ischemia test as part of clinical care
- Suspected coronary artery disease based on clinical symptoms
- Informed Consent as documented by signature
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinic of Radiology & Nuclear Medicine, University Hospital of Basel Coordinator of this site? Confirm its status | Basel | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.