NCT04586972Completed
Safety and Efficacy of Apixaban in Very Old Geriatric Subjects (> 80 Years) With Atrial FIbrillation in a Prospective reAl World Study;
Source: ClinicalTrials.gov · Last updated 16 Sept 2025
Brief summary (registry, in English)
The main objective of this study is to realize an observational "real life" study conducted in French geriatric settings, to assess safety and efficacy in ≥ 80 year-old patients with nonvalvular Atrial fibrillation (AF) newly treated with Apixaban. Moreover, in this geriatric population the adequacy of Apixaban dosage and events (bleeding and stroke) will be assessed.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 977 (actual)
- First submitted
- 25 Sept 2020
- Start date
- 23 Sept 2020
- Primary completion date
- 21 Dec 2023
- Lead sponsor
- Gérond'if
- Diseases
- Atrial fibrillation
- NCT number
- NCT04586972
What you commit to
- Study type: Observational
- Participants enrolled: 977
- From 23 Sept 2020 to the primary completion date, 21 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patient refusing to participate.
- Participation to a clinical trial.
- Contraindication to use of Apixaban as described in the Summary of Product Characteristics .
Who the study is looking for
- Male or female patients aged 80 years and older.
- Patients with non-valvular atrial fibrillation (documented on electrocardiography or other medical evidence like medical chart, hospital discharge note, physician's letter within 3 years before enrollment).
- Followed in geriatric settings (office consultation, acute care, rehabilitation settings and nursing homes).
- Newly treated (less than 6 months) with Apixaban (5mg twice daily (or 2.5 mg twice daily for patients with 2 of the following criteria : age \> 80 years, creatinine \> 133 μmol/l, weight \< 60 kg)
Age in the registry: 80 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Geriatric Department, Broca Hospital Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.