NCT04589247Completed
Improving Cancer On-treatment Symptom Management
Improving Cancer Care by Incorporating the Patient's Voice Into On-treatment Symptom Management
Source: ClinicalTrials.gov · Last updated 25 Sept 2025
Brief summary (registry, in English)
Patient-reported outcome measures (PROMs) is an umbrella term that refers to any report on a health status measure that is reported directly by the patient, without the influence of clinicians or anyone else. PROMs have been shown to more closely reflect a patient's daily health status when compared to physician-reported measures. However, research is needed to evaluate if patient symptom reporting during definitive-intent radiotherapy allows earlier and improved detection of treatment toxicity. The IMPROVE pilot study will describe the proportion of patients with cancer with changes in physician-perception of treatment-related toxicity that result from routine physician review of PROMs reported during definitive radiotherapy.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 104 (actual)
- First submitted
- 6 Oct 2020
- Start date
- 16 Nov 2020
- Primary completion date
- 23 Jul 2023
- Lead sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Diseases
- Lung cancer
- NCT number
- NCT04589247
What you commit to
- Study type: Observational
- Participants enrolled: 104
- From 16 Nov 2020 to the primary completion date, 23 Jul 2023
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients receiving radiation for palliative intent
- Patients who chose to withdraw from the study
- Radiation Oncologists
Other
- Patients who do not provide informed consent
- Have not provided informed consent
Who the study is looking for
- Men and women over 18 years of age
- Able to read and write in English or able to understand/answer questions with the aid of an interpreter
- Histologically confirmed loco-regional to advanced primary cancer, including but not limited to lung cancer, esophageal, or gastro-intestinal cancers at risk of developing radiotherapy-related toxicity.
- Receiving definitive conventionally-fractionated radiation treatment with or without chemotherapy
- Must be the physician overseeing the care of the patient who answers the PROMS
Age in the registry: 18 years to 100 years · Sex: All
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Khinh Voong Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Bayview Medical Center Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Suburban Hospital Coordinator of this site? Confirm its status | Bethesda | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.