NCT04593875Completed
LIFUP for Treatment of Motor Deficits in Parkinson's Disease
Low-Intensity Focused Ultrasound Pulsation for Treatment of Motor Deficits in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 4 Feb 2026
Brief summary (registry, in English)
The study will test the feasibility of using Low Intensity Focused Ultrasound Pulsation (LIFUP) to treat motor symptoms in Parkinson's Disease (PD). LIFUP is a new technique that can increase brain activity in highly specific target areas and is MRI compatible. Thus, in real-time, it is possible to directly observe how LIFUP changes the brain areas important in PD by measuring its effects on brain activity, blood flow, and brain connectivity. If successful, this research will mark the first step towards a novel, non-invasive, non-medication treatment for PD.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 31 (actual)
- First submitted
- 3 Oct 2020
- Start date
- 15 Jun 2022
- Primary completion date
- 24 Jul 2024
- Lead sponsor
- University of California, Los Angeles
- Diseases
- Parkinson disease
- NCT number
- NCT04593875
What you commit to
- Study type: Interventional
- Participants enrolled: 31
- From 15 Jun 2022 to the primary completion date, 24 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Metal implants that are not MR compatible
Other
- Neurological diagnosis other than Parkinson's
- Not fluent in the English language
Who the study is looking for
- Diagnosis of Parkinson's disease
- Age 18-85
- Fluent in the English language
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California, Los Angeles Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.