NCT04604041Recruiting
Investigation of Subclinical Markers of Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 2 Oct 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Transcranial magnetic stimulation (TMS) studies reported consistent and substantial impairments in the central nervous system (CNS) in multiple sclerosis (MS). Studies of peripheral nervous system (PNS) function comprising electromyoneurography (EMNG) reported impairments of the PNS in MS that were less pronounced and inconsistent. Neurophysiological studies are generally small and cross-sectional and with the poor grouping of MS patients according to MS type. The objective of the study is to investigate clinical, neurophysiological, and immunological markers in relapsing-remitting MS patients, and in patients with relapsing-remitting MS treated with immunomodulation. The results of the study may contribute to a better understanding of the pathophysiology of multiple sclerosis and can provide guidance in the diagnosis and treatment of patients with relapsing-remitting MS.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 2 Oct 2020
- Start date
- 23 Nov 2020
- Primary completion date
- Dec 2024
- Lead sponsor
- University of Split, School of Medicine
- Diseases
- Multiple sclerosis
- NCT number
- NCT04604041
What you commit to
- Study type: Observational
- Planned participants: 50
- From 23 Nov 2020 to the primary completion date, Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients with metals in the body (e.g. pacemaker, dentures)
- Patients with new pregnancies (verbally confirmed)
- Patients with new head trauma
- Subjects unwilling to sign a consent or follow study procedures
Who the study is looking for
- Subjects with a documented diagnosis of relapsing-remitting MS according to the Mc Donald criteria (2005) and with EDSS achievement of 0-3.5 according to the modified Kurtzke's EDSS (Expanded disability status scale) for the assessment of neurological function and incapacity of patients with multiple sclerosis
Age in the registry: 18 years to 65 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Split School of Medicine Coordinator of this site? Confirm its status | Split | Croatia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.