NCT04608903Active, not recruiting
Effects of Sulforaphane for Patients With Chronic Kidney Disease
Salutary Effects of Sulforaphane for Patients With Chronic Kidney Disease
Source: ClinicalTrials.gov · Last updated 3 Apr 2025
Brief summary (registry, in English)
Patients with Chronic Kidney Disease (CKD) have many complications associated with inflammation, oxidative stress and intestinal dysbiosis, which are closely related to the progression of kidney failure and cardiovascular disease. Sulforaphane, an isothiocyanate found in cruciferous vegetables (Family: Brassicaceae) is recognized as one of the most important activators of erythroid nuclear factor 2 related to factor 2 (Nrf2). However, clinical evidence to assess the effects of sulforaphane in patients with CKD is scarce, and there are no studies that have investigated its effects on the expression of genes and markers related to inflammation in these patients. Thus, the present project proposes a longitudinal study of the clinical trial type that aims to evaluate the effects of sulforaphane on transcription factors and inflammatory markers in patients with CKD.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 25 Oct 2020
- Start date
- 1 Dec 2021
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Universidade Federal Fluminense
- Diseases
- Chronic kidney disease
- NCT number
- NCT04608903
What you commit to
- Study type: Interventional
- Planned participants: 25
- From 1 Dec 2021 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Autoimmune diseases
- Clinical diagnosis of infectious diseases
- Clinical diagnosis of Cancer
Other
- Patients pregnant
- Smokers
- Using antibiotics in the last 3 months
- Clinical diagnosis of AIDS
Who the study is looking for
- Aged 18 to 75 years
- Clinical diagnosis of Chronic Kidney Disease
- Conservative treatment group: CKD stages 3 and 5 receiving nutritional treatment for at least 6 months
- Hemodialysis group: Hemodialysis patients for more than 6 months
Criteria the registry did not label
- Criteria
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Denise mafra Coordinator of this site? Confirm its status | Rio de Janeiro | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.