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NCT04608903Active, not recruiting

Effects of Sulforaphane for Patients With Chronic Kidney Disease

Salutary Effects of Sulforaphane for Patients With Chronic Kidney Disease

Source: ClinicalTrials.gov · Last updated 3 Apr 2025

Brief summary (registry, in English)

Patients with Chronic Kidney Disease (CKD) have many complications associated with inflammation, oxidative stress and intestinal dysbiosis, which are closely related to the progression of kidney failure and cardiovascular disease. Sulforaphane, an isothiocyanate found in cruciferous vegetables (Family: Brassicaceae) is recognized as one of the most important activators of erythroid nuclear factor 2 related to factor 2 (Nrf2). However, clinical evidence to assess the effects of sulforaphane in patients with CKD is scarce, and there are no studies that have investigated its effects on the expression of genes and markers related to inflammation in these patients. Thus, the present project proposes a longitudinal study of the clinical trial type that aims to evaluate the effects of sulforaphane on transcription factors and inflammatory markers in patients with CKD.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
25 (estimated)
First submitted
25 Oct 2020
Start date
1 Dec 2021
Primary completion date
31 Dec 2023
Lead sponsor
Universidade Federal Fluminense
NCT number
NCT04608903

What you commit to

  • Study type: Interventional
  • Planned participants: 25
  • From 1 Dec 2021 to the primary completion date, 31 Dec 2023
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Autoimmune diseases
  • Clinical diagnosis of infectious diseases
  • Clinical diagnosis of Cancer

Other

  • Patients pregnant
  • Smokers
  • Using antibiotics in the last 3 months
  • Clinical diagnosis of AIDS

Who the study is looking for

  • Aged 18 to 75 years
  • Clinical diagnosis of Chronic Kidney Disease
  • Conservative treatment group: CKD stages 3 and 5 receiving nutritional treatment for at least 6 months
  • Hemodialysis group: Hemodialysis patients for more than 6 months

Criteria the registry did not label

  • Criteria

Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Denise mafra
Coordinator of this site? Confirm its status
Rio de JaneiroBrazilUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.