NCT04611906Completed
Evaluation of Small Vessel Disease by 3D-rotational Angiography
Source: ClinicalTrials.gov · Last updated 24 Feb 2026
Brief summary (registry, in English)
This study is aimed to elucidate the factors affecting the remodeling process of arteriolosclerosis under current practice recommendations. Such knowledge may improve the understanding of cerebral small vessel disease (cSVD) mechanism, define pharmacological therapy and suggest treatment target.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 24 (actual)
- First submitted
- 27 Oct 2020
- Start date
- 5 Nov 2020
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Stroke
- NCT number
- NCT04611906
What you commit to
- Study type: Observational
- Participants enrolled: 24
- From 5 Nov 2020 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Stroke etiology uncertain or unrelated to small vessel disease, such as cardioembolism, Moyamoya disease, ICAD or primary angiitis of CNS.
- A medical condition that would not allow the patient to adhere to the protocol or complete the study.
- Patients with severe renal impairment.
Lab values
- Bleeding propensity: active peptic ulcer disease, major systemic hemorrhage within 30 days, thrombocytopenia (platelets \<100 x 109/L), coagulopathy (INR \>1.5).
Other
- Patients who are taking warfarin and non-vitamin K antagonist oral anticoagulants would also be excluded.
Who the study is looking for
- Patient is Chinese ONLY
- Patient is 30 to 85 years of age, inclusive.
- Patients who have an acute lacunar infarct in diffusion-weighted MRI compatible with small vessel disease in territories supplied by the lateral lenticulostriate arteries without relevant intracranial atherosclerotic stenosis ≥60%.
- Patient who has no contra-indication for the proposed imaging tests.
- Patient who understands the purpose and requirements of the study, and has an informed consent.
- Patient who has Modified Functional Ambulation Classification 4 or above.
Age in the registry: 30 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chinese University of Hong Kong Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.