NCT04614129Completed
Lung Cancer Risk and Early Detection in Firefighters
Source: ClinicalTrials.gov · Last updated 24 Nov 2025
Brief summary (registry, in English)
This study will evaluate whether LDCT findings differ between firefighters and non-fighters, the relationship between occupational exposures and LDCT findings, and whether a proteomics assay can further risk-stratify screen-detected nodules among a study population of 850 current and retired firefighters and 1,120 matched controls.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 734 (actual)
- First submitted
- 28 Oct 2020
- Start date
- 2 Mar 2021
- Primary completion date
- 1 Nov 2025
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Lung cancer
- NCT number
- NCT04614129
What you commit to
- Study type: Interventional
- Participants enrolled: 734
- From 2 Mar 2021 to the primary completion date, 1 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any active cancer (undergoing treatment or diagnosed within the past 5 years)
Who the study is looking for
- 40-80 years of age or with 10 years of firefighting experience
- Current or retired firefighters
- No personal history of lung cancer
- Willing and able to receive LDCT screening at MGH or who have been screened via LDCT within the past year at MGH or another institution, and are willing to release their images to the study
Age in the registry: 40 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.