NCT04618016Active, not recruiting
Evaluation of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee Arthroplasty
Prospective, Randomized, Single-blind, Multinational, Long-term Study for the Evaluation of the Clinical Outcome, Oxidation Profile and Wear Analysis of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee Arthroplasty
Source: ClinicalTrials.gov · Last updated 20 Oct 2026
Brief summary (registry, in English)
Prospective, randomized, single-blind, multinational, long-term study for the evaluation of the clinical outcome, oxidation profile and wear analysis of medium cross-linked Polyethylene with and without Vitamin E for total knee arthroplasty
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 605 (actual)
- First submitted
- 27 Oct 2020
- Start date
- 8 Mar 2021
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Aesculap AG
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT04618016
What you commit to
- Study type: Observational
- Participants enrolled: 605
- From 8 Mar 2021 to the primary completion date, 31 Dec 2024
- 8 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Patient age \< 18 and \> 80 years
Other
- Pregnancy
- High risk patients (ASA class \>3)
Who the study is looking for
- Indication for a total knee replacement with a mobile-bearing UC or PS inlay
- Written informed consent for participating at the clinical study
- Willingness and mental ability to participate at the long-term follow-up examinations
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Park-Klinik Weißensee Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
| Lukas Krankenhaus Coordinator of this site? Confirm its status | Bünde | Germany | Unknown status |
| Waldkliniken Eisenberg Coordinator of this site? Confirm its status | Eisenberg | Germany | Unknown status |
| Brüderhaus Koblenz Coordinator of this site? Confirm its status | Koblenz | Germany | Unknown status |
| Krankenhaus Reinbek, St. Adolf Stift Coordinator of this site? Confirm its status | Reinbek | Germany | Unknown status |
| Universitätsklinikum Rostock, Klinik für Orthopädie Coordinator of this site? Confirm its status | Rostock | Germany | Unknown status |
| Chu Amiens Picardie Coordinator of this site? Confirm its status | Amiens | France | Unknown status |
| Hôpital Sud - CHU de Grenoble Coordinator of this site? Confirm its status | Échirolles | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.