NCT04620278Not yet recruiting
Genetic Investigation of Cancer Predisposition
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
Clinical information and samples (blood, saliva, and tumor) will be collected from patients with multiple cancers and/or a family history of cancer as well as from affected and unaffected relatives; samples will be systematically sequenced and evaluated for candidate driver mutations.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 5 Nov 2020
- Start date
- 1 Oct 2026
- Primary completion date
- 30 Jun 2030
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Diseases
- Childhood cancers
- NCT number
- NCT04620278
What you commit to
- Study type: Observational
- Planned participants: 100
- From 1 Oct 2026 to the primary completion date, 30 Jun 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Established genetic diagnosis of a known hereditary cancer syndrome that is compatible with the clinical presentation
Other
- Incarcerated
Who the study is looking for
- Any age
- Meets at least ONE of the following:
- Personal history (with documented diagnosis) of cancer before the age of 50
- Personal history of more than one primary cancer
- Documented diagnosis of cancer AND family history of that same cancer type or multiple other cancers that do not fit classical criteria of hereditary cancer syndromes
- Documented diagnosis of a rare cancer AND family history of rare cancers that do not fit classical criteria of hereditary cancer syndromes
- There is the same type of cancer in several generations of a family
- Documented diagnosis of multicentric cancers (e.g bilateral cancers in paired organs, or multifocal cancers in single organs) that usually occur as single lesions when presented sporadically
- Early onset cancer (before the age of 50, or breast cancer before age 45) AND family history of early onset cancer Capable of providing access to detailed medical records and family history of cancer
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas Health Science Center Coordinator of this site? Confirm its status | San Antonio | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.