NCT04620538Completed
Volatile Organic Compounds for the Assessment of Liver Disease
Volatile Organic Compounds for the Assessment of Liver Disease: Assessment of Hepatobiliary Disease Through Non-Invasive Detection of Exhaled Volatile Organic Compounds
Source: ClinicalTrials.gov · Last updated 30 Mar 2026
Brief summary (registry, in English)
This study aims to determine whether a breath test could be used for early detection of hepatic fibrosis, cirrhosis or hepatocellular carcinoma. Patients who are attending for a planned liver outpatient services or investigations will be approached to provide a breath sample. Multi platform mass spectrometry analysis will be performed to establish volatile biomarkers that can discriminate between fibrosis, cirrhosis and hepatocellular carcinoma.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 56 (actual)
- First submitted
- 3 Nov 2020
- Start date
- 1 Apr 2021
- Primary completion date
- 25 Mar 2026
- Lead sponsor
- Imperial College London
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT04620538
What you commit to
- Study type: Observational
- Participants enrolled: 56
- From 1 Apr 2021 to the primary completion date, 25 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Any patient outside the established age range (18-90years).
Other
- Patients who lack capacity or unable to provide informed consent.
- Patients unable to fast.
Who the study is looking for
- Patients seen in secondary care with suspected or confirmed liver / pancreatic disease or hepatocellular carcinoma / pancreatic cancer
- Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Imperial College Healthcare Trust Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.