NCT04645212Active, not recruiting
Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]
A Long-term Study of ADVM-022 in Neovascular (Wet) AMD - OPTIC Extension
Source: ClinicalTrials.gov · Last updated 10 Feb 2026
Brief summary (registry, in English)
ADVM-022-07 is an observational long-term extension (OPTIC-EXT) study assessing safety and efficacy of ADVM-022 gene therapy product, in participants with neovascular, or exudative (wet), age-related macular degeneration (nAMD).
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 23 (actual)
- First submitted
- 20 Nov 2020
- Start date
- 14 Dec 2020
- Primary completion date
- 26 Jun 2030
- Lead sponsor
- Adverum Biotechnologies, Inc.
- Diseases
- Macular degeneration
- NCT number
- NCT04645212
What you commit to
- Study type: Observational
- Participants enrolled: 23
- From 14 Dec 2020 to the primary completion date, 26 Jun 2030
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- None
Who the study is looking for
- Participants who received a single dose of ADVM-022 at any dose in the OPTIC study
- Willing and able to provide informed consent
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| - Coordinator of this site? Confirm its status | Bakersfield | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Bellaire | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Beverly Hills | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Deerfield Beach | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Lakewood | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Reno | United States | Unknown status |
| - Coordinator of this site? Confirm its status | The Woodlands | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.