NCT04655963Active, not recruiting
Brain Stimulation for Improving Cognition in Chronic Stroke (NEPTUNE)
Neuromodulation and Plasticity in Cognitive Control Neurocircuitry in Chronic Stroke
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
Few treatments are available for post-stroke rehabilitation. The current study aims to develop a novel, short-term, high-dose repetitive transcranial magnetic stimulation (rTMS) based intervention to improve post-stroke cognitive problems. This study will test the safety as well as changes in cognitive function and brain activation with the administration of an accelerated rTMS protocol in chronic stroke.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 30 Nov 2020
- Start date
- 14 Jan 2021
- Primary completion date
- 30 Dec 2026
- Lead sponsor
- Medical University of South Carolina
- Diseases
- Stroke
- NCT number
- NCT04655963
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 14 Jan 2021 to the primary completion date, 30 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Other concomitant neurological disorders affecting motor or cognitive function
Other illness
- Primary intracerebral hematoma or subarachnoid hemorrhage
- History of seizure disorder
- Substance use disorder
- Psychotic disorders
Other
- Bi-hemispheric ischemic strokes
- Preexisting scalp lesion or wound or bone defect or hemicraniectomy
- Claustrophobia
Who the study is looking for
- Have right hemisphere ischemic or hemorrhagic stroke within last 6 months chronicity
- Able to perform given cognitive tasks
- No metal implanted in the body
- A negative urine pregnancy test, if female subject of childbearing potential.
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.