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NCT04666103Recruiting

Function Integrity of Neck Anatomy in Thyroid Surgery

Preserving Function Integrity of Neck Anatomy in Thyroid Surgery: A Randomized Clinical Trial

Source: ClinicalTrials.gov · Last updated 14 Dec 2020 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment. Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
1264 (estimated)
First submitted
7 Dec 2020
Start date
11 Dec 2020
Primary completion date
31 Dec 2021
Lead sponsor
Wuhan University
NCT number
NCT04666103

What you commit to

  • Study type: Interventional
  • Planned participants: 1264
  • From 11 Dec 2020 to the primary completion date, 31 Dec 2021
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous history of neck surgery
  • Previous history of neck radiation therapy

Who the study is looking for

  • Patients diagnosed with unilateral thyroid carcinoma and contralateral benign nodule confirmed by preoperative ultrasound-guided fine-needle aspiration cytology;
  • Patients with contralateral nodules ≤ 20mm and located in the thyroid gland;
  • Patients with clinical node-negative cervical compartment at palpation and neck ultrasound.

Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Zhongnan Hospital of Wuhan University
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WuhanChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.