NCT04666402Recruiting
Integrated Diagnostics for Early Diagnosis of Liver Disease
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
This is an observational study that will explore the hypothesis that by combining data from patients with liver disease with novel blood biomarkers, single nucleotide polymorphism (SNP) analysis and faecal microbiome analysis. The Investigators will improve diagnosis of liver fibrosis compared to the current available diagnostic tools.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1200 (estimated)
- First submitted
- 21 Oct 2020
- Start date
- 21 Oct 2020
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Manchester University NHS Foundation Trust
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT04666402
What you commit to
- Study type: Observational
- Planned participants: 1200
- From 21 Oct 2020 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known pre-existing liver disease.
- Suspected malignancy.
Lab values
- Pregnancy/breast-feeding. Women of childbearing potential (not \>2 years post- menopausal and/or not surgically sterilised) must have a negative blood serum pregnancy test.
Age
- Age \< 18 years.
Other
- Isolated bilirubinaemia.
- Acutely unwell.
Who the study is looking for
- All patients referred to Community Liver Assessment Clinic.
- Male or female \> 18 years of age.
- Females will be non-pregnant and non-lactating.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Manchester University NHS Foundation Trust Coordinator of this site? Confirm its status | Manchester | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.